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AM03163SU-N  Folate hydrolase 1 (FOLH1/PSMA) antibody

see related secondary antibodies
see all 8 Folate hydrolase 1 products
6 ml / US$ 425
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Rabbit anti Folate hydrolase 1 (FOLH1/PSMA) BV9

Synonyms

FOLH, FOLH1, FOLH-1, NAALAD1, PSM, PSMA, Prostate-specific membrane antigen, EC 3.4.17.21, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, mGCP, , FGCP, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Pteroylpoly-gamma-glutamate carboxypeptidase, Folylpoly-gamma-glutamate carboxypeptidase,

Product Description

Rabbit anti Folate hydrolase 1 (FOLH1/PSMA) BV9, Presentation: Supernatant. Product is tested for Frozen sections ( C ), Paraffin Sections ( P )

Properties

ApplicationsFrozen sections ( C ), Paraffin Sections ( P )
ReactivityHuman ( Hu )
PresentationSupernatant
HostRabbit
IsotypeIgG
CloneBV9
Catalog NumberAM03163SU-N
Swiss Prot. No.Q04609
Quantity6 ml
PriceUS$ 425
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
AM03163SU-N.pdf

Datasheet Extract

BackgroundPMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.
ImmunogenSynthetic peptide from the c-terminus of human PSMA protein
Swiss Num.: Q04609
Format
State: Liquid pretitered IgG
ApplicationsThis antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required. We suggest an incubation period of 30-60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
Positive Control: Prostate carcinoma.
SpecificityThis antibody detects Folate hydrolase 1.
Add. InformationCellular Localization: Membrane.
StorageStore at 2 - 8 °C.
Shelf life: one year from despatch.

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

Click here to see all secondary antibodies for 'AM03163SU-N Folate hydrolase 1 (FOLH1/PSMA)'.