AP00383PU-N MAP kinase 1 / ERK1 / MAPK3 (internal) antibody
see related secondary antibodiessee all 41 MAP kinase 1 / ERK1 / MAPK3 products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti MAP kinase 1 / ERK1 / MAPK3 (internal) -
Synonyms
ERK-1 MAPK1 P44ERK1 P44MAPK PRKM3 ERT2 Mitogen-activated Protein Kinase 3, Extracellular signal-regulated kinase 1, Insulin-stimulated MAP2 kinase, Microtubule-associated protein 2 kinase
Product review
Please read our product review about MAP kinase 1 / ERK1 / MAPK3 (internal): Antibodies to MAP-Kinases.
Product Description
Rabbit anti MAP kinase 1 / ERK1 / MAPK3 (internal) -, Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | AP00383PU-N |
| Swiss Prot. No. | P27361 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AP00383PU-N.pdf |
Datasheet Extract
| Polyclonal Antibody//to Extracellular Signal-Regulated Kinase 1 | |
| Alternate names | MAPK3, MGC20180, P44-ERK1, P44-MAPK, P44ERK1, P44MAPK, PRKM3, EC 2.7.11.24, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, extracellular signal-regulated kinase 1, MITOGEN-ACTIVATED PROTEIN KINASE 3, p44 |
| Concentration | 1 mg/ml |
| Background | ERK1, a MAPK-type protein kinase, is a member of the Ras-MAPK pathway. This pathway modulates the activity of transcription factors, structural proteins, and other protein kinases, leading to biological responses such as cell proliferation and differentiation. Inactive ERK1 associates with MAPK/ERK kinases (MEK) 1 and 2 in the cytosol. Upon stimulation, MEK1/2 phosphorylates and activates ERK1 causing dissociation of the MEK/ERK complex. A portion of the activated ERK1 pool forms dimers and translocates to the nucleus to activate nuclear proteins such as ELK-1 and MSK1. Cytosolic ERK 1 acts on a different set of substrates, including MNK1/2 and MAPKAP-K1. |
| Immunogen | Synthetic peptide corresponding to internal domain of human MAPK - KLH conjugated Genename: MAPK3 Swiss Num.: P27361 |
| Format | State: Liquid Purification: Peptide immunogen affinity column. BufferSystem: Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide. |
| Applications | Immunohistochemistry: 17 µg/ml. |
| Specificity | This antibody detects Extracellular Signal-Regulated Kinase 1. Species: Human. |
| Storage | Store the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. |
| Pictures | Immunohistochemistry Image: Neurons and Glia, stained with AP00383PU-N |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'AP00383PU-N MAP kinase 1 / ERK1 / MAPK3 (internal)'.
