AP00426PU-N Macrophage-Stimulating 1 Receptor (MST1R/Ron) (internal) antibody
see related secondary antibodiessee all 6 Macrophage-Stimulating 1 Receptor products
50 µg / US$ 515
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti Macrophage-Stimulating 1 Receptor (MST1R/Ron) (internal)
Synonyms
P185-RON, PTK8, cd136, cdw136, fv2, msp receptor, mst1r, stk,
Product Description
Rabbit anti Macrophage-Stimulating 1 Receptor (MST1R/Ron) (internal) , Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | AP00426PU-N |
| Quantity | 50 µg |
| Price | US$ 515 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AP00426PU-N.pdf |
Datasheet Extract
| Alternate names | MST1R, cd136 antigen, cdw136, Friend virus susceptibility 2, fv2, macrophage stimulating 1 receptor (c-met-related tyrosine kinase), macrophage-stimulating protein receptor, msp receptor, mst1r, oncogene RON, p185-ron, RON, stk |
| Concentration | 0.7 mg/ml |
| Background | MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers. |
| Immunogen | Synthetic peptide, correponding to the internal domain of human MST1R - KLH conjugated Genename: MST1R |
| Format | State: Liquid Purification: Peptide immunogen affinity column. BufferSystem: Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide. |
| Applications | Immunohistochemistry on paraffin embedded sections: 3 µg/ml. |
| Specificity | This antibody detects Macrophage-Stimulating 1 Receptor.
Mouse Identity: 22 % Mouse Similarity: 28 % Species: Human, Mouse. |
| Storage | Store the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. |
| Pictures | Immunohistochemistry Image: Colon, surface pithelium, stained with AP00426PU-N |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
