AP00522PU-N c-erbB-4 / Her-4 antibody
see related secondary antibodiessee all 27 c-erbB-4 / Her-4 products
0.5 mg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti c-erbB-4 / Her-4
Synonyms
p180erbB4, c-erbB4, HER4, Receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell surface receptor HER4
Product Description
Rabbit anti c-erbB-4 / Her-4 , Presentation: Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | AP00522PU-N |
| Swiss Prot. No. | Q15303 |
| Quantity | 0.5 mg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AP00522PU-N.pdf |
Datasheet Extract
| Concentration | 1 mg/ml |
| Background | c-erbB-4 is the fourth member of class I receptor kinase family (ErbB). HER-4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum. Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDA-MB-330 and MDA-MB-361. Expression of erbB-4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3. |
| Immunogen | A synthetic peptide (aa 1285-1308) from the C-terminus of human c-erbB-4/HER-4 oncoprotein. Swiss Num.: Q15303 |
| Format | State: Liquid Purification: Protein A affinity purified immunoglobulin fraction BufferSystem: 10mM PBS pH 7.4 with 0.09% sodium azide as preservative and 0.2% BSA as stabilizer. |
| Applications | Western Blot. Recommended positive control: T47D or MDA-MB-453 Cells. |
| Specificity | Higly specific for c-erbB-4 / HER-4. No reactivity with other family members observed so far. Cellular Localization: Cytoplasmic, Cell Membrane. Mol. Wt. of Antigen: 185kD. Species: Human, Rat, and Mouse. |
| Storage | Store at 2-8°C for up to one month or in aliquots at -20°C for longer. Avoid repeated freeze thaw cycles! Shelf life: one year from despatch. |
| References | 1. Chen X, et. al. J Biol Chem, 1996, 271(13):7620-9.
2. Tang C, et. al. Cancer Res. 1999 Oct 15; 59(20):5315-22. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'AP00522PU-N c-erbB-4 / Her-4'.
