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AP02803SU-N  AGER / RAGE antibody

see related secondary antibodies
see all 25 AGER / RAGE products
0.1 ml / US$ 695
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Goat anti AGER / RAGE

Synonyms

Receptor for Advanced Glycosylation End products, , Advanced glycosylation end product-specific receptor, AGE Receptor, MGC22357

Product review
Please read our product review about AGER / RAGE: AGE – Advanced Glycation End Products.

Product Description

Goat anti AGER / RAGE , Presentation: Serum. Product is tested for Paraffin Sections ( P ), Enzyme Immunoassay ( E ), Western blot / Immunoblot ( WB )

Properties

ApplicationsParaffin Sections ( P ), Enzyme Immunoassay ( E ), Western blot / Immunoblot ( WB )
ReactivityBovine ( Bov ), Human ( Hu ), Mouse ( Ms ), Rat ( Rt )
PresentationSerum
HostGoat
Catalog NumberAP02803SU-N
Swiss Prot. No.Q15109
Quantity0.1 ml
PriceUS$ 695
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
AP02803SU-N.pdf

Datasheet Extract

Alternate namesReceptor for Advanced Glycation End Products
BackgroundLong-term incubation of proteins with glucose leads, through Schiff's base and Amadori rearrangement products, to the formation of advanced glycation end products (AGE).
RAGE, the receptor for AGE is a member of the immunoglobulin superfamily and is exprimed e.g. by endothelial cells, mononuclear phagocytes, smooth muscle cells and neurons.
RAGE and the deposition of AGE is involved in a number of pathologigical conditions such as nephropathy, Alzheimer's disease and arteriosclerosis.
ImmunogenSynthetic peptide corresponding to human RAGE (42-59)
Swiss Num.: Q15109
AA Sequence: 42PKKPPQRLEWKLNTGRTE59
Format
State: Liquid serum containing 0.01% Merthiolate as a preservative
ApplicationsAntibody AP02803SU-N is suitable for the detection of RAGE in tissues and tissue extracts.
Recommended dilutions:
Immunohistochemistry on paraffin embedded tissues (1:400): in immunohistochemistry formalin-fixed tissues are pretreated preferentially with citrate buffer for 15-30 min at 100°C.
Western blot (1:2000).
ELISA (1:260000).
Renal tissue is recommended as positive control.
SpecificityThe antibody recognizes human Receptor for Advanced Glycation End Products (RAGE).
Due to amino acid sequence homology cross-reactivity with bovine, rat and mouse can be expected.
StorageStore (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
ReferencesSchmidt AM, Hori O, Cao R, Yan SD, Brett J, Wautier JL, Ogawa S, Kuwabara K, Matsumoto M, Stern D.
RAGE: a novel cellular receptor for advanced glycation end products. Diabetes. 1996 Jul;45 Suppl 3:S 77-80. Review.

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1317B Goat IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 295
   
R1317F Goat IgG (H&L)  
  Rabbit FITC   2 mg / US$ 295
   
R1317T Goat IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 295
   
R1317TR Goat IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1317HRP Goat IgG (H&L)  
  Rabbit HRP   2 mg / US$ 305
   
R1317AP Goat IgG (H&L)  
  Rabbit AP   1 mg / US$ 315
   
R1435C2 Goat IgG (H&L) multi-species ads.  
  Donkey Cy2   1 mg / US$ 445
   
R1435C3 Goat IgG (H&L) multi-species ads.  
  Donkey Cy3   1 mg / US$ 445
   
R1435C35 Goat IgG (H&L) multi-species ads.  
  Donkey Cy3.5   1 mg / US$ 445
   
R1435C5 Goat IgG (H&L) multi-species ads.  
  Donkey Cy5   1 mg / US$ 465
   
R1435C55 Goat IgG (H&L) multi-species ads.  
  Donkey Cy5.5   1 mg / US$ 445
   
R1416R Goat IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

Click here to see all secondary antibodies for 'AP02803SU-N AGER / RAGE'.