AP07270PU-N V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) antibody
see related secondary antibodiessee all 5 V-Akt Murine Thymoma Viral Oncogene Homolog 1 products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
Synonyms
AKT1, C-AKT, EC 2.7.11.1, MGC99656, PKB, PRKBA, RAC, RAC-ALPHA, RAC-PK-ALPHA,
Product Description
Rabbit anti V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) , Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | AP07270PU-N |
| Swiss Prot. No. | P31749 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AP07270PU-N.pdf |
Datasheet Extract
| Background | AKT1 encodes a RAC/AKT-type protein kinase that contains a N-terminal pleckstrin-homology (PH) domain and a central catalytic domain closely related to both cAMP-dependent protein kinase and protein kinase C. The protein is a member of PI3K-mediated signaling pathways associated with the regulation of proliferation, survival, protein synthesis, and metabolism. It is phosphorylated by 3'-phosphoinositide-dependent kinase-1 (PDK1) in response to stimulation by growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and insulin. Activated AKT1 has been shown to phosphorylate and inactivate components of the apoptotic machinery. AKT1 (-/-) mice have been shown to be viable but smaller than wild-type littermates, and they have a reduced lifespan and increased spontaneous apoptosis in several tissues when exposed to stressors. AKT1 protein is the cellular homolog of the product of the retroviral oncogene v-akt, and has been implicated in numerous cancers. |
| Immunogen | Synthetic peptide Swiss Num.: P31749 |
| Format | State: Liquid purified Ig Purification: Immunoaffinity Chromatography BufferSystem: Phosphate buffered saline, containing 0.02% sodium azide |
| Applications | Western Blot: 1,0 µg/ml.
Immunohistochemistry: 5 µg/ml. |
| Specificity | This antibody reacts to a 16 amino acid peptide from near the amino-terminus of Akt1. Species: Human. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Pictures | Adrenal: Formalin-Fixed Paraffin-Embedded (FFPE) |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 305 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 295 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 295 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 305 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 305 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 335 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 455 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 455 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 455 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 455 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 455 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 465 | |||||