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Product Description for LYPD3 / C4.4A
Ly6/PLAUR domain-containing protein 3, GPI-anchored Metastasis-associated Protein Homolog
Properties for LYPD3 / C4.4A
| Manufacturer | Acris Antibodies GmbH |
| Quantity | 50 µg |
| Reactivity | Human |
| Presentation | Aff - Purified |
| Applications | Paraffin Sections |
| Isotype | IgG |
| Host | Rabbit |
| PDF datasheet | view  |
| Shipping to | Not USA/Canada |
Datasheet Extract
| Synonyms | C4.4A, MIG-C4 |
| Immunogen | Synthetic peptide KLH conjugated. LYPD3 antibody was raised against C-terminal domain of Human LYPD3 |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format | State: Liquid purified Ig fraction. |
| Purification: Immunoaffinity Chromatography. | |
| Buffer System: PBS containing 0.09% Sodium Azide as preservative. | |
| Specificity | This antibody recognizes GPI-anchored Metastasis-associated Protein Homolog (C4.4A) (LYPD3). |
| Application | Immunohistochemistry on Paraffin Sections: 15 µg/ml. This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. |
| Background | C4.4A is a structural homolog of the urokinase-type plasminogen activator receptor (uPAR). It was originally identified as a metastasis-associated membrane protein in malignant urothelium. In literature IHC studies, staining has been observed in suprabasal keratinocytes of chronic wounds and the amniotic membrane of placenta. ISH analysis demonstrated expression in urothelium of the ureter. C4.4A expression has also been found to be upregulated in breast tumors when compare to normal breast tissue. |
| Concentration | 0.6 mg/ml |
| Species Reactivity | Tested: Human. |
Secondary Antibodies for LYPD3 / C4.4A
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / 190 Euro | |||||
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / 160 Euro | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / 160 Euro | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / 170 Euro | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / 160 Euro | |||||
| R1427R | Rabbit IgG F(ab)2 Fragment | ||||||
| Donkey | PE | 1 ml / 290 Euro | |||||
| R1458C2 | Rabbit IgG (H&L) | ||||||
| Goat | Cy2 | 1 mg / 250 Euro | |||||
| R1458C3 | Rabbit IgG (H&L) | ||||||
| Goat | Cy3 | 1 mg / 250 Euro | |||||
| R1458C5 | Rabbit IgG (H&L) | ||||||
| Goat | Cy5 | 1 mg / 250 Euro | |||||
