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Product Description for CYLD
Properties for CYLD
| Manufacturer | Acris Antibodies GmbH |
| Quantity | 50 µg |
| Reactivity | Human |
| Presentation | Aff - Purified |
| Applications | Immunofluorescence, Paraffin Sections, Western blot / Immunoblot |
| Isotype | IgG |
| Host | Rabbit |
| PDF datasheet | view  |
| Shipping to | Not USA/Canada |
Datasheet Extract
| Synonyms | CYLD, CYLD1, KIAA0849, Ubiquitin carboxyl-terminal hydrolase CYLD, EC=3.1.2.15, Ubiquitin thioesterase CYLD, Ubiquitin-specific-processing protease CYLD, Deubiquitinating enzyme CYLD |
| Immunogen | CYLD antibody was raised against Human. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format | State: Liquid purified Ig fraction. |
| Purification: Affinity Chromatography. | |
| Buffer System: PBS containing 1% BSA as stabilizer and 0.02% Sodium Azide as preservative. | |
| Specificity | This antibody recognizes Cylindromatosis (turban Tumor Syndrome) (CYLD). |
| Application | Immunohistochemistry on Paraffin Sections: 20 µg/ml. Immunocytochemistry: 1/200. Western blot: 1/3000. Agonist (Agon). |
| Background | Defects in CYLD are the cause of familial cylindromatosis (CYLD) also known as turban tumor syndrome or dermal eccrine cylindromatosis. CYLD is an autosomal dominant and highly tumor type-specific disorder. The tumors (known as cylindromas because of their characteristic microscopic architecture) are believed to arise from or recapitulate the appearance of the eccrine or apocrine cells of the skin that secrete sweat and scent respectively. Cylindromas arise predominantly in hairy parts of the body with approximately 90% on the head and neck. The development of a confluent mass which may ulcerate or become infected has led to the designation "turban tumor syndrome". The skin tumors show differentiation in the direction of hair structures, hence the synonym trichoepithelioma. CYLD has deubiquitinating activity. |
| Concentration | 0.45 mg/ml |
| Species Reactivity | Tested: Human. |
Secondary Antibodies for CYLD
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / 190 Euro | |||||
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / 160 Euro | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / 160 Euro | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / 170 Euro | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / 160 Euro | |||||
| R1427R | Rabbit IgG F(ab)2 Fragment | ||||||
| Donkey | PE | 1 ml / 290 Euro | |||||
| R1458C2 | Rabbit IgG (H&L) | ||||||
| Goat | Cy2 | 1 mg / 250 Euro | |||||
| R1458C3 | Rabbit IgG (H&L) | ||||||
| Goat | Cy3 | 1 mg / 250 Euro | |||||
| R1458C5 | Rabbit IgG (H&L) | ||||||
| Goat | Cy5 | 1 mg / 250 Euro | |||||
