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AP09064PU-N: Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE)

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AP09064PU-N CYLD antibody

Rated with 4 stars
see related secondary antibodies
search for all CYLD
50 µg / €360.00
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Delivery time: 5-7 workingdays
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Quick Overview

Rabbit anti Human CYLD

Product Description for CYLD

Properties for CYLD

ManufacturerAcris Antibodies GmbH
Quantity50 µg
ReactivityHuman
PresentationAff - Purified
ApplicationsImmunofluorescence, Paraffin Sections, Western blot / Immunoblot
IsotypeIgG
HostRabbit
PDF datasheetview datasheet
Shipping toNot USA/Canada

Datasheet Extract

SynonymsCYLD, CYLD1, KIAA0849, Ubiquitin carboxyl-terminal hydrolase CYLD, EC=3.1.2.15, Ubiquitin thioesterase CYLD, Ubiquitin-specific-processing protease CYLD, Deubiquitinating enzyme CYLD
Immunogen CYLD antibody was raised against Human.
Product TypeAntibodies
StorageStore the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
FormatState: Liquid purified Ig fraction.
 Purification: Affinity Chromatography.
 Buffer System: PBS containing 1% BSA as stabilizer and 0.02% Sodium Azide as preservative.
Specificity This antibody recognizes Cylindromatosis (turban Tumor Syndrome) (CYLD).
ApplicationImmunohistochemistry on Paraffin Sections: 20 µg/ml.
Immunocytochemistry: 1/200.
Western blot: 1/3000.
Agonist (Agon).
BackgroundDefects in CYLD are the cause of familial cylindromatosis (CYLD) also known as turban tumor syndrome or dermal eccrine cylindromatosis. CYLD is an autosomal dominant and highly tumor type-specific disorder. The tumors (known as cylindromas because of their characteristic microscopic architecture) are believed to arise from or recapitulate the appearance of the eccrine or apocrine cells of the skin that secrete sweat and scent respectively. Cylindromas arise predominantly in hairy parts of the body with approximately 90% on the head and neck. The development of a confluent mass which may ulcerate or become infected has led to the designation "turban tumor syndrome". The skin tumors show differentiation in the direction of hair structures, hence the synonym trichoepithelioma.
CYLD has deubiquitinating activity.

Concentration0.45 mg/ml
Species ReactivityTested: Human.

Secondary Antibodies for CYLD

Catalog No.Name / HostPresentationReactivity 
R1364AP Rabbit IgG (H&L)
  Goat AP 1 mg / 190 Euro
   
R1364B Rabbit IgG (H&L)
  Goat Biotin 2 mg / 160 Euro
   
R1364F Rabbit IgG (H&L)
  Goat FITC 2 mg / 160 Euro
   
R1364HRP Rabbit IgG (H&L)
  Goat HRP 2 mg / 170 Euro
   
R1364T Rabbit IgG (H&L)
  Goat TRITC 2 mg / 160 Euro
   
R1427R Rabbit IgG F(ab)2 Fragment
  Donkey PE 1 ml / 290 Euro
   
R1458C2 Rabbit IgG (H&L)
  Goat Cy2 1 mg / 250 Euro
   
R1458C3 Rabbit IgG (H&L)
  Goat Cy3 1 mg / 250 Euro
   
R1458C5 Rabbit IgG (H&L)
  Goat Cy5 1 mg / 250 Euro
   
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