AP09382PU-N ODF2 pSer796 antibody

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0.1 mg / €320.00
Delivery Time: 5-7 working days

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Rabbit anti Chimpanzee, Human, Monkey ODF2

AP09382PU-N

Product Description for ODF2

Rabbit anti Chimpanzee, Human, Monkey ODF2.
Properties: pSer796
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for ODF2

Product Category Antibodies
Quantity 0.1 mg
Synonyms Cenexin, Outer dense fiber of sperm tails protein 2, Outer dense fiber protein 2
Presentation Aff - Purified
Reactivity Chimp, Hu, Mky
Applications E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
Q5BJF6
Immunogen:
Synthetic peptide corresponding to residues near S796 of human cenexin-1
Genename:
4957
Property pSer796
Antibody type Ab
Application ELISA: 1/2,000 - 1/10,000.
Western Blot: 1/200 - 1/2,000.
Background Cenexin-1, also known as ODF2 and outer dense fiber of sperm tails 2, are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. Cenexin-1 is one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of the cenexin gene; however, not all isoforms and variants have been fully described.
Concentration 0.8 mg/ml (by UV absorbance at 280 nm)
General Readings
  • Soung NK, Kang YH, Kim K, Kamijo K, Yoon H, Seong YS, et al. Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes. Mol Cell Biol. 2006 Nov;26(22):8316-35. Epub 2006 Sep 11. PubMed PMID: 16966375.
  • Kierszenbaum AL. Keratins: unraveling the coordinated construction of scaffolds in spermatogenic cells. Mol Reprod Dev. 2002 Jan;61(1):1-2. PubMed PMID: 11774369.
  • Petersen C, Füzesi L, Hoyer-Fender S. Outer dense fibre proteins from human sperm tail: molecular cloning and expression analyses of two cDNA transcripts encoding proteins of approximately 70 kDa. Mol Hum Reprod. 1999 Jul;5(7):627-35. PubMed PMID: 10381817.
  • Hoyer-Fender S, Petersen C, Brohmann H, Rhee K, Wolgemuth DJ. Mouse Odf2 cDNAs consist of evolutionary conserved as well as highly variable sequences and encode outer dense fiber proteins of the sperm tail. Mol Reprod Dev. 1998 Oct;51(2):167-75. PubMed PMID: 9740324.
  • Shao,X., Murthy,S., Demetrick,D.J. and van der Hoorn,F.A. (1998) Human outer dense fiber gene, ODF2, localizes to chromosome 9q34. Cytogenet. Cell Genet. 83 (3-4), 221-223.
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01% (w/v) Sodium Azide
State:
Liquid
Aff - Purified
Species Reactivity
Species reactivity (expected):
Chimpanzee, Macaque.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody is specific for Cenexin-1 protein phosphorylated at S796.
Gene ID 4957
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for ODF2 (2 products)

Catalog No. Species Pres. Purity   Source  
H00004957-Q01-10

ODF2

ODF2 Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00004957-Q01-25

ODF2

ODF2 Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for ODF2 (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-13908

ODF2 Lysate

Western Blot: ODF2 Lysate [NBL1-13908] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ODF2
0.1 mg / €370.00
  Novus Biologicals Inc.