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AR01016PU-S  Betacellulin antigen


see all 18 Betacellulin products
5 µg / US$ 255
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Human Betacellulin

Synonyms

Probetacellulin, BTC,

Product Description

Human Betacellulin

Properties

PresentationPurified
SpeciesHuman
Purity>98%
SourceE. coli
Catalog NumberAR01016PU-S
Swiss Prot. No.P35070
Quantity5 µg
PriceUS$ 255
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
AR01016PU-S.pdf

Datasheet Extract

BackgroundBetacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence.
Immunogen
Swiss Num.: P35070
SourceE. coli
Format
State: Lyophilized protein
Purity: > 98 % by SDS-PAGE gel and HPLC analyses
Endotoxinlevel: < 0.1 ng per ?g (1EU/?g)
DescriptionRecombinant human Betacellulin is a monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
AASequence: DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is < 0.05 ng/ml, corresponding to a specific activity of > 2 x 10E7units/mg.
Molecular weight: 9.0 kDa
StorageStore the lyophilized protein at -20 °C. Following reconstitution product is stable for 3 months when stored in working aliquots with a carrier protein at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.