AR01018PU-N Bone Morphogenetic Protein 4 (BMP4) antigen
see all 11 Bone Morphogenetic Protein 4 products
5 µg / US$ 355
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Human Bone Morphogenetic Protein 4 (BMP4)
Synonyms
BMP-4, BMP2B, DVR4,
Product Description
Human Bone Morphogenetic Protein 4 (BMP4)
Properties
| Presentation | Purified |
| Species | Human |
| Purity | >97% |
| Source | HeLa-229 cells |
| Catalog Number | AR01018PU-N |
| Quantity | 5 µg |
| Price | US$ 355 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AR01018PU-N.pdf |
Datasheet Extract
| Alternate names | DVR4 |
| Background | Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. |
| Source | HeLa cells |
| Format | State: Lyophilized protein Purity: > 97 % by SDS-PAGE gel and HPLC analyses Endotoxinlevel: < 0.1 ng per ?g (1EU/?g) |
| Description | Recombinant human BMP-4, is a homodimeric glycoprotein. AASequence: HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. Molecular weight: 31-36 kDa |
| Storage | Store the lyophilized protein at -20 °C. Following reconstitution product is stable for 3 months when stored in working aliquots with a carrier protein at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. |
| References | Pick M, Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis Stem Cells. ;25(9):2206-14 9/1/2007 17556598 |
