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AR01018PU-S  Bone Morphogenetic Protein 4 (BMP4) antigen


see all 11 Bone Morphogenetic Protein 4 products
1 µg / US$ 255
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Human Bone Morphogenetic Protein 4 (BMP4)

Synonyms

BMP-4, BMP2B, DVR4,

Product Description

Human Bone Morphogenetic Protein 4 (BMP4)

Properties

PresentationPurified
SpeciesHuman
Purity>97%
SourceHeLa-229 cells
Catalog NumberAR01018PU-S
Quantity1 µg
PriceUS$ 255
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
AR01018PU-S.pdf

Datasheet Extract

Alternate namesDVR4
BackgroundBone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.
SourceHeLa cells
Format
State: Lyophilized protein
Purity: > 97 % by SDS-PAGE gel and HPLC analyses
Endotoxinlevel: < 0.1 ng per ?g (1EU/?g)
DescriptionRecombinant human BMP-4, is a homodimeric glycoprotein.
AASequence: HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR
Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
Molecular weight: 31-36 kDa
StorageStore the lyophilized protein at -20 °C. Following reconstitution product is stable for 3 months when stored in working aliquots with a carrier protein at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
ReferencesPick M, Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis Stem Cells. ;25(9):2206-14 9/1/2007 17556598