AR03028PU-N Herbimycin A Inhibitor antigen
see all 2 Herbimycin A Inhibitor products
1 mg / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Herbimycin A Inhibitor
Product Description
Herbimycin A Inhibitor
Properties
| Presentation | Purified |
| Purity | >98% |
| Molecular Weight | 574.3 |
| Catalog Number | AR03028PU-N |
| Quantity | 1 mg |
| Price | please contact our distributor |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AR03028PU-N.pdf |
Datasheet Extract
| Background | Herbimycin A, a benzoquinoid ansamycin antibiotic, irreversibly and selectively inhibits tyrosine kinases by reacting with thiol groups (1,2). It is effective on Src, Yes, Fps, Ros, Abl and ErbB oncogene products (1-3) and inhibits thrombin-induced tyrosine phosphorylation of phospholipase C (4). |
| Source | Synthetic |
| Format | State: Lyophilized solid; yellow Purity: 98% Reconstitution: Soluble in DMSO and ethanol (1 mg/ml) |
| Description | Formula: C30H42N2O9 Molecular weight: 574.3 |
| Storage | Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
Avoid repeated freezing and thawing. Protect from light! Shelf life: One year from despatch. |
| Protocols | 1. Uehara Y.,and Fukazawa H. (1991) Methods Enzymol. 201: 370.
2. Fukazawa H., et al. (1991) Biochem. Pharmacol. 42: 1661. 3. Satoh T., et al.(1992) J.Biol.Chem. 267: 2537. 4. Weiss R., and Nuccitelli R. (1992) J.Biol.Chem. 267:5608. |
| Pictures | Figure 1: Structure of Herbimycin |
