BM3358 CD227 / Mucin-1 antibody
see related secondary antibodiessee all 70 CD227 / Mucin-1 products
1 mg / US$ 645
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse anti CD227 / Mucin-1 552
Synonyms
CA15-3, MUC-1, Polymorphic epithelial mucin, PEM, PEMT, Episialin, Tumor-associated mucin, Carcinoma-associated mucin, EMA, H23AG, PUM, Tumor-associated epithelial membrane antigen, nut-reactive urinary mucin, Breast carcinoma-associated antigen DF3
Product Description
Mouse anti CD227 / Mucin-1 552, Presentation: Purified. Product is tested for Frozen sections ( C ), Enzyme Immunoassay ( E ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Enzyme Immunoassay ( E ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | 552 |
| Catalog Number | BM3358 |
| Swiss Prot. No. | P15941 |
| Quantity | 1 mg |
| Price | US$ 645 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  BM3358.pdf |
Datasheet Extract
| Alternate names | Mucin 1, MUC1 |
| Concentration | 2.5 mg/ml (OD280 nm, E0.1% = 1.35) |
| Background | The MUC-1 mucin (Cancer Antigen CA15-3) is secreted from tumor cells. The apo-protein of the MUC-1 mucin contains a transmembrane domain, a cytoplasmic domain, and an extracellular carbohydrate rich domain. The extracellular domain is characterized by polymorphism with respect to the number of a 20 amino acid tandem repeat (VNTR polymorphism). |
| Immunogen | Human breast cancer cell line ZR 75-1. Swiss Num.: P15941 |
| Format | State: Liquid purified Ig fraction Purification: Protein A chromatography. BufferSystem: 0.15 M Sodium Chloride without preservative. |
| Applications | Capture or detection antibody in serological assays for the research of antigen MUC-1. This antibody forms a suitable pair with Clone 695. Immunohistochemistry on frozen or paraffin sections for the detection of MUC-1.
Immunochemical detection of MUC-1 protein. |
| Specificity | Specific for the tandem repeat of the MUC-1 core.
Recognizes the hexapeptide (TRPAPG). |
| Add. Information | IgG > 99% of total peak area (Superdex 200 gel chromatography on Ã?ktaFPLC). |
| Storage | Store the antibody at 2-8°C for one month or at -20°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Hilkens J., et al., (1984), J. Int J. Cancer, 34, 197.
2. Baeckstrom D., et al., (1993), Discrimination of MUC1 mucins from other Sialyl-Lea-carrying glyco-proteins by colon carcinoma cells using a novel monoclonal antibody, Cancer Res., 53, 755. 3. Nilsson O., et al., (1994), Development of assays for determination of MUC-1 breast cancer antigen, 7th Symposium on Tumors Markers, Hamburg 1993, R Klapdor (ed) Current Tumor Diagnostics: Applications, Clinical Relevance, Research, Trends. W. Zuckerwerdt Verlag Munchen. 4. Nilsson O., et al., (1994), Novel Mab for determination of breast cancer associated MUC-1 mucin antigen. XXII International Society for Oncodevelopment Biology and Medicine, Groningen 5. Perey L. et al., (1992), Tumor Selective Reactivity of a Monoclonal Antibody Prepared against a Recombinant Peptide Derived from the DF3 Human Breast Carcinoma-associated Antigen. Cancer Reasearch 52, 2563-2568. May 1, 1992. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 315 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 295 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 295 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 305 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 325 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 335 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 455 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 455 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 455 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 455 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 455 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 465 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 465 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 465 | |||||
Click here to see all secondary antibodies for 'BM3358 CD227 / Mucin-1'.
