BP170 Protein Gene Product 9.5 (PGP9.5) antibody
see related secondary antibodiessee all 30 Protein Gene Product 9.5 products
50 µl / US$ 435
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti Protein Gene Product 9.5 (PGP9.5)
Synonyms
UCHL1 - ubiquitin carboxyl-terminal esterase L1, PARK5, , ubiquitin thiolesterase
Product Description
Rabbit anti Protein Gene Product 9.5 (PGP9.5) , Presentation: Serum. Product is tested for Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mamalia ( Mam ) |
| Presentation | Serum |
| Host | Rabbit |
| Catalog Number | BP170 |
| Quantity | 50 µl |
| Price | US$ 435 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  BP170.pdf |
Datasheet Extract
| Background | PGP 9.5 hydrolyses a peptide bond at the C-terminal glycine of the proteolysis tagging protein ubiquitin, thereby generating/recycling ubiquitin monomers, essential in the ubiquitin-proteasome cytoplasmic protein degradation system. PGP 9.5 is a focus area for neurological disorders such as Alzheimer's and Parkinson's disease and has been linked with tumour invasion and progression. |
| Immunogen | Native, from brain |
| Format | State: Liquid neat serum BufferSystem: 0.02 % sodium azide |
| Applications | Immunohistochemistry on paraffin sections (1:200 - 1:800; Antigen retrieval using heat treatment may enhance staining; sodium citrate buffer pH 6.0 is recommended
for this purpose.) Western blot (1:1000 - 1:5000; detects a band of approximately 27 kDa in rat brain cell lysates). |
| Specificity | This antibody specifically stains protein gene product 9.5 (PGP 9.5), a 27 kDa ubiquitin-protein hydrolase, expressed in the cytoplasm of neurons and cells of the diffuse neuroendocrine system and related tumours. Species: Human, Guinea Pig, Rabbit, Hamster, Pig, Sheep, Cat, Mouse, Bovine, Rat, Dog. |
| Storage | Store the antibody at -20 °C. Ship at 2 - 8 °C.
Avoid repeated freezing and thawing. Shelf life: One year from despatch. |
| References | 1. Xue, L. et al. (2000) Carbon monoxide and nitric oxide coneurotransmitters in the enteric nervous system: Evidence from genomic deletion of biosynthetic enzymes. P.N.A.S. 97: 1851-1855.
2. Adolfsson, P.I. et al. (2000) Changes in beta2-adrenoreceptor expression and in adenylyl cyclase and phosphodiesterase activity in human uterine leiomyomas. Mol. Hum. Repro. 6: 835-842. 3. Hibi, K. et al. (1999) PGP9.5 as a candidate tumor marker for non-small-cell lung cancer. Am. J. Pathol. 155: 711-715. 4. Yamazaki, T. et al. (2002) PGP9.5 as a marker for invasive colorectal cancer. Clin. Cancer Res. 8: 192-195. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 305 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 295 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 295 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 305 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 305 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 335 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 455 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 455 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 455 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 455 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 455 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 465 | |||||
Click here to see all secondary antibodies for 'BP170 Protein Gene Product 9.5 (PGP9.5)'.
