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BP4505  Lamin C antibody

see related secondary antibodies
see all 2 Lamin C products
0.2 ml / US$ 525
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Rabbit anti Lamin C

Synonyms

filament-type protein,

Product Description

Rabbit anti Lamin C , Presentation: Aff - Purified. Product is tested for Frozen sections ( C ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )

Properties

ApplicationsFrozen sections ( C ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu ), Mouse ( Ms ), Rat ( Rt )
PresentationAff - Purified
HostRabbit
Catalog NumberBP4505
Quantity0.2 ml
PriceUS$ 525
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
BP4505.pdf

Datasheet Extract

BackgroundNuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2.
ImmunogenA peptide made from the last 8 amino acids of lamin C, including an N-terminal lysine as a linker (KHHVSGSRR), coupled to KLH
Format
State: Liquid Ig fraction containing 0.09% sodium azide
Purification: Affinity chromatography
ApplicationsImmunofluorescence.
Flow cytometry: 1/50 - 1/250.
Immunohistochemistry on frozen sections: 1/50 - 1/250, ABC.
Immunoblotting: 1/50 - 1/500.
SpecificityThis antibody reacts exclusively with Lamin C.

Species: Human, mouse and rat.
StorageStore at 2-8°C for up to one month or in small aliquots at -20°C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
References1. Venables, R. S., McLean, S., Luny, D., Moteleb, E., Morley, S., Quinlan, R. A., Lane, E. B., and Hutchison, C. J. (2001). Expression of individual lamins in basal cell carcinomas of the skin, Br J Cancer 84, 512-9.
2. Tilli, C. M., Ramaekers, F. C., Broers, J. L., Hutchison, C. J., and Neumann, H. A. (2003). Lamin expression in normal human skin, actinic keratosis, squamous cell carcinoma and basal cell carcinoma. Br J Dermatol 148, 102-109.
3. Broers, J. L., Bronnenberg, N. M., Kuijpers, H. J., Schutte, B., Hutchison, C. J., and Ramaekers, F. C. (2002). Partial cleavage of A-type lamins concurs with their total
disintegration from the nuclear lamina during apoptosis. Eur J Cell Biol 81, 677-691.

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 305
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 295
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 295
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 305
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 305
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 335
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 455
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 455
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 455
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 455
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 455
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 465
   

Click here to see all secondary antibodies for 'BP4505 Lamin C'.