DA3502 BMP2 antigen
see all 28 BMP2 products
5 µg / US$ 255
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Human BMP2
Synonyms
Bone Morphogenetic Protein 2, BMP-2, BMP-2A, BMP2A, Bone Morphogenetic Protein 1, Procollagen C-Proteinase, Mammalian Tolloid Protein
Product Description
Human BMP2
Properties
| Presentation | Purified |
| Species | Human |
| Purity | >95% |
| Source | E. coli |
| Molecular Weight | 26 kD |
| Catalog Number | DA3502 |
| Swiss Prot. No. | P12643 |
| Quantity | 5 µg |
| Price | US$ 255 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  DA3502.pdf |
Datasheet Extract
| Background | BMP-2 regulates similiarly to its nearest homologue BMP-4 diverse fundamental processes during embryonic development: BMP-2 and other BMP proteins have great potential for medical therapeutic applications, in particular because they allow or at least accelerate the ossification of extensive bone lesions. BMP-2 is a heparin binding protein. |
| Immunogen | Swiss Num.: P12643 |
| Source | E. coli |
| Format | State: Lyophilised Purity: > 95% by SDS-PAGE and visualised by silver stain BufferSystem: None, contains no stabiliser Endotoxinlevel: < 0.1 ng per µg of BMP-2 Reconstitution: The lyophilised BMP-2 is soluble in distilled water and most aqueous buffers at concentrations greater than 1.0 mg/ml when the pH is below 6.0. Above pH 6.0 the solubility is low, but could be increased by addition of 1 M NaCl or 30% 2-propanol. |
| Description | Human Bone Morphogenetic Protein-2 (BMP-2) is a disulfide-bonded homodimeric protein.
BMP-2 lacks the natural N-terminus which results in a 15-20 fold increase of specific activity. Biological Activity: Measured by the ability of BMP-2 to induce alkaline phosphatase production by C2C12 myogenic cells. The ED50 for this effect is typically 0.3-0.8 µg/ml. Specific Activity: 2.5 x 10e3 units/mg Molecular weight: 26 kDa |
| Storage | Lyophilised samples are stable for six months from despatch at -20°C to -70°C.
Reconstituted BMP-2 should be stored in working aliquots at -20°C. Avoid repeated freezing and thawing. |
| References | 1. Wozney et al., Science 242:1528, 1988.
2. Ruppert et al., Eur J Biochem 237:295, 1996. |