Human Thrombopoietin (TPO) DA3549S - antibody, protein, elisa from Acris Antibodies ...

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2 µg / US$ 215

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Human Thrombopoietin (TPO)

Mpl-ligand, MGDF,

Human Thrombopoietin (TPO)


Alternate names	Thrombopoietin
Background	TPO (Thrombopoietin, Mpl-ligand, and MGDF) produced in E. coli is a single, non-glycosylated soluble protein containing 174 amino acids and having a molecular mass of 18.6 kDa which comprises the receptor binding domain of the Mpl-ligand protein. TPO stimulates the proliferation and maturation of megakaryocytes and promotes increased circulation levels of platelets in vivo.
Source	E. coli
Format	*State:* Lyophilized without buffer and stabilizer. *Purity:* > 98% by RP-HPLC, Anion-exchange FPLC, Silver stain *Endotoxinlevel:* < 0.1 ng per �g (IEU/�g) of rh TPO. *Reconstitution:* Restore in sterile water.
Description	*Biological Activity:* Human rh TPO is fully biologically active when compared to standards. The ED50 was determined by the dose-dependent stimulation of the proliferation of human MO7e cells is < / = 1.0 ng/ml. *Specific Activity:* 1 x 10e6 units/mg *Molecular weight:* 18.6 kDa
Add. Information	Centrifuge vials before opening!
Storage	Store lyophilized rh TPO at -20°C. Reconstituted rh TPO should be stored in working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA). Avoid repeated freeze-thaw cycles! Shelf life: One year from despatch.


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