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DA3549X  Thrombopoietin (TPO) antigen


see all 19 Thrombopoietin products
50 µg / US$ 605
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Human Thrombopoietin (TPO)

Synonyms

Mpl-ligand, MGDF,

Product Description

Human Thrombopoietin (TPO)

Properties

PresentationPurified
SpeciesHuman
Purity>98%
SourceE. coli
Molecular Weight18.6 kD
Catalog NumberDA3549X
Quantity50 µg
PriceUS$ 605
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
DA3549X.pdf

Datasheet Extract

Alternate namesThrombopoietin
BackgroundTPO (Thrombopoietin, Mpl-ligand, and MGDF) produced in E. coli is a single, non-glycosylated soluble protein containing 174 amino acids and having a molecular mass of 18.6 kDa which comprises the receptor binding domain of the Mpl-ligand protein. TPO stimulates the proliferation and maturation of megakaryocytes and promotes increased circulation levels of platelets in vivo.
SourceE. coli
Format
State: Lyophilized without buffer and stabilizer.
Purity: > 98% by RP-HPLC, Anion-exchange FPLC, Silver stain
Endotoxinlevel: < 0.1 ng per µg (IEU/µg) of rh TPO.
Reconstitution: Restore in sterile water.
Description
Biological Activity: Human rh TPO is fully biologically active when compared to standards.
The ED50 was determined by the dose-dependent stimulation of the proliferation of human MO7e cells is < / = 1.0 ng/ml.
Specific Activity: 1 x 10e6 units/mg
Molecular weight: 18.6 kDa
Add. InformationCentrifuge vials before opening!
StorageStore lyophilized rh TPO at -20°C.
Reconstituted rh TPO should be stored in working aliquots at -20°C.
For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA).
Avoid repeated freeze-thaw cycles!
Shelf life: One year from despatch.