DP3500 Lymphatic vessel endothelial hyaluronic acid receptor 1 antibody
see related secondary antibodiessee all 20 Lymphatic vessel endothelial hyaluronic acid receptor 1 products
0.1 mg / US$ 355
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti Lymphatic vessel endothelial hyaluronic acid receptor 1
Synonyms
LYVE1, CRSBP1, HAR, XLKD1, LYVE-1, , Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1
Product Description
Rabbit anti Lymphatic vessel endothelial hyaluronic acid receptor 1 , Presentation: Purified. Product is tested for Frozen sections ( C ), Enzyme Immunoassay ( E ), Flow cytometry ( F ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Enzyme Immunoassay ( E ), Flow cytometry ( F ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | DP3500 |
| Swiss Prot. No. | Q9Y5Y7 |
| Quantity | 0.1 mg |
| Price | US$ 355 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  DP3500.pdf |
Datasheet Extract
| Background | LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosamino-glycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels. |
| Immunogen | Recombinant human soluble LYVE-1 (24-232) produced in insect cells. The recombinant soluble LYVE-1 consists of amino acid 24 (Ser) to 232 (Gly) and is fused to a C-terminal His-tag (6xHis). Swiss Num.: Q9Y5Y7 |
| Format | State: Lyophilized IgG Purification: Protein A chromatography (+ his tag depleted) BufferSystem: PBS, pH 7.4 Reconstitution: Restore in sterile water to a concentration of > 0.5 mg/ml. |
| Applications | ELISA (1-15 µg/ml).
Western blot (1-2 µg/ml). FACS (3-20 µg/ml). Immunohistochemistry on frozen sections (6-30 µg/ml). Please note: For use on paraffin embedded sections the affinity-purified antibody (DP3500PS) is recommended. |
| Specificity | The antibody recognizes LYVE-1. Species: Human. |
| Storage | The lyophilized IgG is stable at 2-8°C for one month and for one year from despatch when kept at -20°C.
When reconstituted to a concentration of > 0.5 mg/ml the antibody is stable for six weeks at 2-8°C and at -20°C for longer. Aliquot to avoid repeated freezing and thawing. |
| References | Carriera et al., Cancer Res 61:8079, 2001.
Jackson DG Trends Cardiovasc Med 13:1, 2003. Sleeman et al., Microsc Res Tech 55:61, 2001. Mäkinen et al., EMBO J 20: 4762, 2001. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
