GTX10389 Macrophage Inflammatory Protein 3 beta antibody
see related secondary antibodiessee all 2 Macrophage Inflammatory Protein 3 beta products
50 µg / no delivery possible
Quick Overview
Goat anti Macrophage Inflammatory Protein 3 beta
Product Description
Goat anti Macrophage Inflammatory Protein 3 beta , Presentation: Aff - Purified. Product is tested for Enzyme Immunoassay ( E ), Neutralisation ( NEUT ), Western blot / Immunoblot ( WB )
Properties
| Applications | Enzyme Immunoassay ( E ), Neutralisation ( NEUT ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ) |
| Presentation | Aff - Purified |
| Host | Goat |
| Isotype | IgG |
| Catalog Number | GTX10389 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| Macrophage Inflammatory Protein 3 beta antibody | |
| Concentration | 0.1 mg/ml |
| Background | MIP3 chemokines are among many novel beta chemokines recently identified through bioinformatics in the Expressed Sequence Tag (EST) database. They are distantly related to other beta chemokines (20-30% aa sequence homology). MIP3 chemokines are useful probes for studying the biology of inflammation and cell migration. Their expression is strongly up-regulated by inflammatory signals and down-regulated by the antiinflammatory cytokine IL10. MIP3 genes do not share chromosomal locations with other beta chemokines that are mainly clustered on chromosome 17. MIP3 alpha is also known as LARC (liver and activation regulated chemokine) and as exodus. It is expressed predominately in lymph nodes, appendix, PBL, fetal liver, fetal lung and some cell lines. Synthetic or recombinant MIP3 alpha has been shown to be chemotactic for cultured human lymphocytes and to inhibit proliferation of myeloid progenitors in colony formation assays. MIP3 alpha binds to the chemokine receptor CCR6. The MIP3 alpha gene has been mapped to chromosome 2. MIP3 beta is also known as ELC (EBI1-1 ligand chemokine) and is constitutively expressed in various lymphoid tissues (thymus, lymph nodes, appendix and spleen). MIP3 beta is a chemoattractant for cultured human lymphcytes, dendritic cells, human Tlymphoblastoid CEM NKR2 and hemopoietic progenitor cells. It may be involved in G Protein activation in human NK cells. MIP3 beta is a unique functional ligand for CCR7. The MIP3 beta gene has been mapped to chormosome 9p13. |
| Immunogen | Purified recombinant mouse MIP-3beta expressed in E. coli. |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Preservative: NoneConstituents: PBS |
| Applications | ELISA, Neut, WB |
| Specificity | Cross-reacts with Human and Mouse. Not yet tested in other species. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1317B | Goat IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1317F | Goat IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 305 | |||||
| R1317T | Goat IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 305 | |||||
| R1317TR | Goat IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 305 | |||||
| R1317HRP | Goat IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1317AP | Goat IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1435C2 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy2 | 1 mg / US$ 455 | |||||
| R1435C3 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3 | 1 mg / US$ 455 | |||||
| R1435C35 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3.5 | 1 mg / US$ 455 | |||||
| R1435C5 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5 | 1 mg / US$ 485 | |||||
| R1435C55 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5.5 | 1 mg / US$ 455 | |||||
| R1416R | Goat IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 465 | |||||
Click here to see all secondary antibodies for 'GTX10389 Macrophage Inflammatory Protein 3 beta'.
