GTX10580 Protein jagged-1 antibody
see related secondary antibodiessee all 7 Protein jagged-1 products
25 µg / no delivery possible
Quick Overview
Goat anti Protein jagged-1
Synonyms
JAG1 JAGL1 JAG-1 JAGL-1 Jagged1 hJ1 CD339 antigen
Product Description
Goat anti Protein jagged-1 , Presentation: Aff - Purified. Product is tested for Enzyme Immunoassay ( E ), Flow cytometry ( F ), Neutralisation ( NEUT ), Westernblot / Immunoblot ( WB )
Properties
| Applications | Enzyme Immunoassay ( E ), Flow cytometry ( F ), Neutralisation ( NEUT ), Westernblot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Goat |
| Isotype | IgG |
| Catalog Number | GTX10580 |
| Swiss Prot. No. | P78504 |
| Quantity | 25 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| Jagged 1 antibody | |
| Concentration | 0.1 mg/ml |
| Background | Jagged 1 is a notch ligand. The Notch signaling system regulates proliferation, differentiation and apoptosis in many tissues, including hematopoietic tissue. Notch is a family of transmembrane receptors activated by ligands such as jagged 1, jagged 2 and delta 1 that are expressed on adjacent cells. Hematopoietic stem cells and early progenitors express notch 1 and notch 2, whereas primary stromal cultures have been shown to express jagged 1, indicating that jagged 1 may play a role in nurturing progenitor cells within the hematopoietic microenvironment. Cells engineered to express high levels of jagged 1 caused a four-fold increase in formation of hematopoietic progenitor cell colonies. However, without the presence of other cytokines that stimulate proliferation and maturation, such as IL3, IL6, SCF and GCSF, jagged 1 actually decreased myeloid colony formation by CD34+ cells, suggesting that jagged 1 modulates cytokine signals and helps preserve CD34+ cells in an immature state. |
| Immunogen | Recombinant rat jagged-1 extracellular domain expressed in mouse NSO cells. Swiss Num.: P78504 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Preservative: None Constituents: PBS |
| Applications | ELISA, FACS, Neut, WB |
| Specificity | Human and Rat. Not yet tested in other species. |
| Storage | Aliquot and store at -20 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1317B | Goat IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / 170,00 € | |||||
| R1317F | Goat IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / 170,00 € | |||||
| R1317T | Goat IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / 170,00 € | |||||
| R1317TR | Goat IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / 170,00 € | |||||
| R1317HRP | Goat IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / 180,00 € | |||||
| R1317AP | Goat IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / 190,00 € | |||||
| R1435C2 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy2 | 1 mg / 320,00 € | |||||
| R1435C3 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3 | 1 mg / 320,00 € | |||||
| R1435C35 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3.5 | 1 mg / 320,00 € | |||||
| R1435C5 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5 | 1 mg / 340,00 € | |||||
| R1435C55 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5.5 | 1 mg / 320,00 € | |||||
| R1416R | Goat IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / 330,00 € | |||||
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