JNK-associated leucine-zipper protein GTX12331

Mitogen-activated protein kinase 8-interacting protein 4, C-jun-amino-terminal kinase-interacting protein 4

Synonyms	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1, JIP-4, JLP, Sperm-associated antigen 9,, JNK-interacting protein 4
Swiss Prot Num	O60271
Immunogen	Immunogen was a synthetic peptide, which represented a portion of human JLP encoded within exon 1.
Product Type	Antibodies
Storage	Keep as concentrated solution. Store at 4
Format	Purity: Immunogen affinity purified
	Purification: Immunogen affinity purified
	Buffer System: Preservative: 0.1% Sodium Azide; Constituents: Tris-citrate/phosphate. pH 7-8
Specificity	Cross-reacts with Human. Expected to cross-react with Mouse due to complete sequence identity between this ortholog and the peptide used for antibody production. Not yet tested in other species.
Application	WB
Background	Extracellular signals are transduced into cells through mitogen-activated protein kinases. The structural organization of these kinases into specific signaling domains is facilitated by scaffolding proteins involved in closely tethering different kinases so that successive phosphorylation events can occur. JLP is a scaffolding protein that brings together mitogen-activated protein kinases and their transcription factor targets for the activation of specific signaling pathways. JLP is abundantly expressed in testicular haploid germ cells and is recognized by sperm-agglutinating antibodies and implicated in infertility.
Concentration	1 mg/ml