GTX16899 CD340 / ERBB2 antibody
see related secondary antibodiessee all 104 CD340 / ERBB2 products
100 µg / no delivery possible
Quick Overview
Mouse anti CD340 / ERBB2 9G6
Synonyms
CD340, ERBB2, HER2, NEU, NGL, EC 2.7.10.1, p185erbB2, C-erbB-2, NEU proto-oncogene, MLN 19, , Tyrosine kinase-type cell surface receptor HER2, Receptor tyrosine-protein kinase erbB-2
Product Description
Mouse anti CD340 / ERBB2 9G6, Presentation: Aff - Purified. Product is tested for Frozen sections ( C ), Immunoprecipitation ( IP ), Paraffin Sections ( P )
Properties
| Applications | Frozen sections ( C ), Immunoprecipitation ( IP ), Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | 9G6 |
| Catalog Number | GTX16899 |
| Swiss Prot. No. | P04626 |
| Quantity | 100 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet | http://www.genetex.com/co ... |
Datasheet Extract
| c-ErbB2 antibody [9G6] | |
| Concentration | 0.1 mg/ml |
| Background | neu (from neuroglioblastomas) is also referred to as erbB-2 (from erythroblastosis virus) and HER2 (for Human Epidermal growth factor Receptor) and is the second member of the EGF receptor family to be described.The human proto-oncogene c-ErbB2/c-neu is upregulated in approximately 30%of breast carcinomas, this amplification maybe useful as a predictor of disease prognosis. Gene amplification and the resulting overexpression of proto-oncogene encoded proteins is thought to transform cells by chronically stimulating signal transduction pathways. Indeed overexpression of human c-ErbB2/c-neu induces cellular transformation. In rat models, a point mutation has been located within the transmembrane domain of the c-ErbB2/c-neu oncogene. |
| Immunogen | Cells overexpressing the human c-ErbB2/c-Neu antigen Swiss Num.: P04626 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Preservative: 0.1% Sodium Azide. Constituents: 0.2% Gelatin, 50mM Sodium phosphate buffer |
| Applications | IHC-Fr, IHC-P, IP |
| Specificity | Cross-reacts with Human.Expected to cross-react with Dog (87% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| Storage | Keep as concentrated solution. Store at 4 |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
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