GTX16901 CD340 / ERBB2 antibody
see related secondary antibodiessee all 104 CD340 / ERBB2 products
100 µg / no delivery possible
Quick Overview
Mouse anti CD340 / ERBB2 3B5
Synonyms
CD340, ERBB2, HER2, NEU, NGL, EC 2.7.10.1, p185erbB2, C-erbB-2, NEU proto-oncogene, MLN 19, , Tyrosine kinase-type cell surface receptor HER2, Receptor tyrosine-protein kinase erbB-2
Product Description
Mouse anti CD340 / ERBB2 3B5, Presentation: Ig Fraction. Product is tested for Frozen sections ( C ), Frozen sections ( C ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Frozen sections ( C ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ) |
| Presentation | Ig Fraction |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | 3B5 |
| Catalog Number | GTX16901 |
| Swiss Prot. No. | P04626 |
| Quantity | 100 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| c-ErbB2 antibody [3B5] | |
| Concentration | 0.1 mg/ml |
| Background | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. |
| Immunogen | Synthetic peptide: TAENPEYLGLDVPV, corresponding to C terminal amino acids 1242 - 1255 of Human c-ErbB2. Swiss Num.: P04626 |
| Format | Purification: IgG fraction Purity: IgG fraction BufferSystem: Preservative: 0.1% Sodium Azide. Constituents: 0.2% Gelatin, 50mM Sodium phosphate buffer |
| Applications | IF, IHC-F, IHC-Fr, IHC-P, IP, WB |
| Specificity | Cross-reacts with Human and Mouse.Expected to cross-react with Dog (87% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| Storage | Keep as concentrated solution, aliquot and store at 4 |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'GTX16901 CD340 / ERBB2'.
