GTX22338 COX1 / PTGS1
see related secondary antibodiessee all 17 COX1 / PTGS1 products
100 µg / no delivery possible
Quick Overview
Goat anti COX1 / PTGS1
Synonyms
Prostaglandin-endoperoxide synthase 1 PGHS-1 PHS 1 COX-1 FocusOn121 Prostaglandin G/H synthase 1, Cyclooxygenase-1, Prostaglandin H2 synthase 1, PGH synthase 1
Product Description
Goat anti COX1 / PTGS1 , Presentation: Ig Fraction. Product is tested for Westernblot / Immunoblot ( WB )
Properties
| Applications | Westernblot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Ig Fraction |
| Host | Goat |
| Isotype | IgG |
| Catalog Number | GTX22338 |
| Swiss Prot. No. | P23219 |
| Quantity | 100 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| COX1 / Cyclooxygenase 1 antibody | |
| Concentration | 0.5 mg/ml |
| Background | Cyclooxygenase (COX), also known as Prostaglandin H2 synthase and Prostaglandin endoperoxide synthase, is a key enzyme in the of conversion arachidonic acid to Prostaglandin H2. Prostaglandin H2 is converted by other enzymes into inflammatory mediators prostaglandin (PG) D2, PGE2, PGF2a, PGI2 and Thromboxane A2. Thus, COX is a key enzyme in the production of inflammatory agents and is the target of intense research and drug discovery activities. There are two enzymes of COX, COX-1 and COX-2. COX-1 is constitutively produced in many (most) cell types. It is important in the gut for the production of prostaglandins, which inhibit gastric secretion. It can be induced in monocytes, macrophages and other cells. It is induced as part of the inflammatory response by IL-1beta and other cytokines. It is induced by growth factors such as EGF and PDGF. Expression is inhibited by glucocorticosteroids such as cortisol and dexamethasone. Lipopolysaccharide in bacterial infections induces COX-2. COX-2 is also found in elevated levels in synoviocytes from rheumatoid arthritis patients. The discomforts of inflammation such as pain and swelling are largely due to the action of prostaglandins produced by COX-2. |
| Immunogen | Peptide with sequence QDDGPAVERPSTEL, from C Terminus of the protein sequence according to NP_000953; NP_542158 Swiss Num.: P23219 |
| Format | State: Liquid Purification: IgG fraction Purity: IgG fraction BufferSystem: Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA |
| Applications | WB |
| Specificity | Human - Not yet tested in other species |
| Storage | Upon receipt - Keep as concentrated solution. Aliquot and store at -20 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1317B | Goat IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / 170,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1317F | Goat IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / 170,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1317T | Goat IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / 170,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1317TR | Goat IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / 170,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1317HRP | Goat IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / 180,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1317AP | Goat IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / 190,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1435C2 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy2 | 1 mg / 320,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1435C3 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3 | 1 mg / 320,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1435C35 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3.5 | 1 mg / 320,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1435C5 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5 | 1 mg / 340,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1435C55 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5.5 | 1 mg / 320,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
| R1416R | Goat IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / 330,00 Euro | |||||
| Acris Antibodies GmbH | |||||||
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