GTX22784 ABCC7 / CFTR antibody
see related secondary antibodiessee all 16 ABCC7 / CFTR products
100 µl / no delivery possible
Quick Overview
Mouse anti ABCC7 / CFTR CF3
Synonyms
Cystic fibrosis transmembrane conductance regulator, cAMP-dependent chloride channel
Product review
Please read our product review about ABCC7 / CFTR: Antibody Panel for the Detection of Cystic fibrosis transmembrane conductance regulator (CFTR).
Product Description
Mouse anti ABCC7 / CFTR CF3, Presentation: Ascites. Product is tested for Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Westernblot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Westernblot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ) |
| Presentation | Ascites |
| Host | Mouse |
| Isotype | IgM |
| Clone | CF3 |
| Catalog Number | GTX22784 |
| Swiss Prot. No. | P13569 |
| Quantity | 100 µl |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| CFTR antibody [CF3] | |
| Background | Cystic Fibrosis (CF) is a common lethal genetic disease caused by mutations of the gene coding for the cystic fibrosis transmembrane conductance factor, a cAMP regulated chloride channel. Approximately 70% of all CF cases share the deletion of a phenylalanine at position 508 (delta F508), which results in abnormal chloride transport. Since the CF mutation is lethal, most often by lung and liver disease, it raises the question of why this genetic disease remains as common as it is. One possible explanation is that Salmonella typhi has been shown to use CFTR to enter intestinal epithelial cells and that delta F508 heterozygote and homozygote mice showed 86% and 100% reductions in S. typhi intestinal submucosal uptake. |
| Immunogen | Synthetic peptide : G(103)RIIASYDPDNKEER(117). Immunizing peptide corresponds to amino acid residues 103-117 found in the first extracellular loop of human and rabbit CFTR. This sequence is highly conserved in mouse, sheep, cow, and Xenopus laevis. Swiss Num.: P13569 |
| Format | State: Liquid Purification: Ascites Purity: Ascites BufferSystem: Diluted ascites with sodium azide |
| Applications | IF, IP, WB |
| Specificity | Cross-reacts with Human and Mouse. Not yet tested in other species. |
| Storage | Upon receipt - Keep as concentrated solution. Aliquot and store at -20 |
10 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1349B | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 355 | |||||
| R1349F | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 335 | |||||
| R1349T | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 335 | |||||
| R1349TR | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 355 | |||||
| R1349HRP | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 365 | |||||
| R1349AP | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | AP | 1 mg / US$ 385 | |||||
| SP1018F | Mouse IgM mu chain | ||||||
| Goat | FITC | Ms | 1 mg / US$ 375 | ||||
| SP1018R | Mouse IgM mu chain | ||||||
| Goat | PE | Ms | 0.1 mg / US$ 485 | ||||
| SP1018HRP | Mouse IgM mu chain | ||||||
| Goat | HRP | Ms | 1 mg / US$ 385 | ||||
| SP1018AP | Mouse IgM mu chain | ||||||
| Goat | AP | Ms | 0.8 mg / US$ 425 | ||||
Click here to see all secondary antibodies for 'GTX22784 ABCC7 / CFTR'.
