GTX22809 TGN38 / TGOLN2 antibody
see related secondary antibodiessee all 12 TGN38 / TGOLN2 products
100 µl / no delivery possible
Quick Overview
Mouse anti TGN38 / TGOLN2 2F7.1
Synonyms
Golgi Marker, TGN46, TGN48, TGN51, , TGN Marker, Trans-Golgi Network Integral Membrane Protein, Trans-Golgi Network Protein TGN51
Product review
Please read our product review about TGN38 / TGOLN2: Antibody Panel useful as specific Marker for the Golgi Apparatus.
Product Description
Mouse anti TGN38 / TGOLN2 2F7.1, Presentation: Ascites. Product is tested for Flow cytometry ( F ), Immunofluorescence ( IF ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Flow cytometry ( F ), Immunofluorescence ( IF ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Rat ( Rt ) |
| Presentation | Ascites |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | 2F7.1 |
| Catalog Number | GTX22809 |
| Swiss Prot. No. | P19814 |
| Quantity | 100 µl |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| TGN38 antibody [2F7.1]-TGN Marker | |
| Background | The trans-Golgi network (TGN) is part of the secretory pathway of eukaryotic cells which is distinct from the Golgi stack. The TGN is important in the later stages of protein secretion where it seems to play a key role in the sorting and targeting of secreted proteins to the correct destination. Some surface receptors recycle between the cell surface and the TGN, suggesting that the TGN is also important in endocytic pathways. TGN 38 and TGN 41, an isoform of the former, are integral membrane proteins which are predominantly localized to the TGN in NRK cells but which can also be observed at the cell surface. Complexes which include TGN 38, low molecular weight G proteins and p62 are required for the formation of TGN-derived vesicles. This requirement has lead people to believe that TGN 38 is important in the trafficking of proteins from the TGN to the cell surface. Brefeldin A causes the contents of the Golgi stack to be redistributed into the endoplasmic reticulum while the TGN collapse upon the microtubule organizing center. This makes immunofluorescence detection of TGN 38 following brefeldin A treatment a useful tool for the discrimination of the TGN from the Golgi stack. |
| Immunogen | Synthetic peptide: LPSASKPNNTSSENNPP-C, corresponding to amino acids 1-17 of Rat TGN38. Swiss Num.: P19814 |
| Format | State: Liquid Purification: Ascites Purity: Ascites BufferSystem: PBS with 0.05% sodium azide |
| Applications | FACS, ICC, IF, WB |
| Specificity | Cross-reacts with Rat. Not yet tested in other species. |
| Storage | Keep as concentrated solution. Store at 4 |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'GTX22809 TGN38 / TGOLN2'.
