GTX22999 FAK1 / PTK2 antibody
see related secondary antibodiessee all 23 FAK1 / PTK2 products
500 µl / no delivery possible
Quick Overview
Rabbit anti FAK1 / PTK2
Synonyms
Protein-Tyrosine kinase 1, FAK, pp125FAK, FADK 1, , PTK2 protein tyrosine kinase 2, FADK-1, FADK, Focal adhesion kinase 1, FAK-1
Product review
Please read our product review about FAK1 / PTK2 : Antibodies to Focal Adhesion Kinase (FAK).
Product Description
Rabbit anti FAK1 / PTK2 , Presentation: Purified. Product is tested for Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | GTX22999 |
| Swiss Prot. No. | Q05397 |
| Quantity | 500 µl |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| FAK antibody | |
| Concentration | 1 mg/ml |
| Background | FAK (Focal Adhesion Associated Protein-Tyrosine Kinase) is a widely expressed non receptor protein tyrosine kinase (PTK). FAK has a central catalytic domain and a C terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors. Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin. Adhesion of murine NIH3T3 fibroblasts to fibronectin promotes association of the Grb 2 adapter protein and c Src PTK with FAK in vivo, and also results in activation of the ERK 2 MAP kinase. In v-Src-transformed NIH3T3, the association of v-Src, Grb 2, and Sos with FAK is independent of cell adhesion to fibronectin. In vitro the Grb 2 SH2 domain binds directly to tyrosine phosphorylated FAK, and the binding site has been identified as Tyr 925 by site directed mutagenesis. |
| Immunogen | Recombinant fragment, corresponding to amino acids 853-1052 of Human FAK. Swiss Num.: Q05397 |
| Format | State: Liquid Purification: Protein A purified Purity: Protein A purified BufferSystem: 10mM Phosphate-buffered saline containing 0.2%BSA and 0.1% sodium azide |
| Applications | IF, WB |
| Specificity | Human, Mouse, and Rat - Not yet tested in other species |
| Storage | Keep as concentrated solution, aliquot and store at 4 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'GTX22999 FAK1 / PTK2 '.
