GTX26103 DFF45 / ICAD / DFFA Control Peptide antigen
see all 10 DFF45 / ICAD / DFFA Control Peptide products
50 µg / no delivery possible
Quick Overview
DFF45 / ICAD / DFFA Control Peptide
Synonyms
Inhibitor of CAD DFF-45 DFF1 DNA fragmentation factor subunit alpha, DNA fragmentation factor 45 kDa subunit
Product review
Please read our product review about DFF45 / ICAD / DFFA Control Peptide: Antibodies to DNA Fragmentation Factor: DFF40 (CAD) and DFF45 (ICAD).
Product Description
DFF45 / ICAD / DFFA Control Peptide ;Is tested for Flow cytometry (F)
Properties
| Catalog Number | GTX26103 |
| Swiss Prot. No. | O54786 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| ICAD peptide | |
| Concentration | 0.2 mg/ml |
| Background | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A human DNA fragmentation factor (DFF) was identified recently which was cleaved by caspase-3 during apoptosis. Mouse homologue of human DFF was identified as a DNase inhibitor designated ICAD, for inhibitor of caspase-activated DNase. Upon cleavage of DFF/ICAD, a caspase activated deoxyribonuclease (CAD) is released and activated and eventually causes the degradation of DNA in the nuclei. Therefore, the cleavage of CAD inhibitor molecule DFF/ICAD, which causes DNase activation and DNA degradation, is the hallmark of apoptotic cell death. |
| Immunogen | Swiss Num.: O54786 |
| Format | Purification: n/a Purity: n/a BufferSystem: Preservative: 0.02% Sodium Azide; Constituents: 0.1% BSA, PBS. pH 7.2 |
| Applications | BL |
