GTX28391 Beta-secretase 2 Control Peptide antigen
see all 6 Beta-secretase 2 Control Peptide products
50 µg / no delivery possible
Quick Overview
Beta-secretase 2 Control Peptide
Synonyms
Aspartyl protease 1, Memapsin-1, BACE2, AEPLC, ALP56, ASP21, ASP1, ASP 1, Memapsin 1, Beta-site APP-cleaving enzyme 2, Membrane-associated aspartic protease 1, Aspartic-like protease 56 kDa, Down region aspartic protease
Product Description
Beta-secretase 2 Control Peptide
Properties
| Catalog Number | GTX28391 |
| Swiss Prot. No. | Q9Y5Z0 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| BACE2 peptide | |
| Concentration | 0.2 mg/ml |
| Background | Accumulation of the abeta in plaques in the cerebral cortex is a critical event in the pathogenesis of Alzheimers disease. Abeta peptide is generated by proteolytic cleavage of the b-amyloid protein precursor(APP) at by secretases. BACE/Asp2 is a novel transmembrane aspartic protease and co-localizes with APP. A BACE homolog was cloned and designated BACE2, Asp1, DRAP (for Down region aspartic protease), and memapsin 1. BACE2 also cleaves APP at b-site and at a different site within Ab. BACE2 locates on chromosome 21q22.3, the so-called Down critical region, suggesting that BACE2 and Ab may also contribute to the pathogenesis of Down syndrome. |
| Immunogen | Swiss Num.: Q9Y5Z0 |
| Format | Purification: n/a Purity: n/a BufferSystem: PBS with 0.1% BSA 0.02% sodium azide pH7.2 |
| Applications | BL |
| Storage | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20 |
