GTX28398 BCL10 antibody
see related secondary antibodiessee all 21 BCL10 products
100 µg / no delivery possible
Quick Overview
Rabbit anti BCL10
Synonyms
B-cell CLL/lymphoma 10, Bcl-10, CIPER, CLAP, hCLAP, mE10, c-E10, cCARMEN, Cellular-E10, CED-3/ICH-1 prodomain homologous E10-like regulator, CARD-containing molecule enhancing NF-kappa-B, Mammalian CARD-containing adapter molecule E10
Product Description
Rabbit anti BCL10 , Presentation: Ig Fraction. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Ig Fraction |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | GTX28398 |
| Swiss Prot. No. | O95999 |
| Quantity | 100 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| Bcl10 antibody | |
| Concentration | 0.5 mg/ml |
| Background | Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and Caspase-2. A novel CARD containing protein was recently identified by several groups and designatedBcl10, CIPER, mE10, CARMEN, CLAP (1-6). Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10gene. Overexpression of Bcl10 induces JNK, p38, and NF-kB activation (1,2,4,6). Bcl10 interacts withcaspase-9 and enhances pro-caspase-9 processing (3) and induces Apoptosis through caspase-9activation (3.6). BCL10 exhibits a variety of mutations in MALT lymphomas and in B and T cell lineage lymphomas indicating that it may be commonly involved in the pathogenesis of human malignancy (1,5). BCL10 is expressed in many human and murine tissues and cell lines (2-6). |
| Immunogen | Synthetic peptide, corresponding to amino acids 5-19 of Human Bcl10. Swiss Num.: O95999 |
| Format | Purification: IgG fraction Purity: IgG fraction BufferSystem: PBS with 0.02% sodium azide |
| Applications | WB |
| Specificity | Human - Not yet tested in other species |
| Storage | Keep as concentrated solution, aliquot and store at 4 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 305 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 295 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 295 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 305 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 305 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 335 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 455 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 455 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 455 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 455 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 455 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 465 | |||||
Click here to see all secondary antibodies for 'GTX28398 BCL10'.
