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GTX29009  Laminin antibody

see related secondary antibodies
see all 136 Laminin products
1 ml / no delivery possible
please contact the manufacturer
GeneTex Inc.
San Antonio, TX, USA
www.genetex.com

Quick Overview

Sheep anti Laminin

Product Description

Sheep anti Laminin , Presentation: Ig Fraction. Product is tested for Dot blot ( Dot ), Western blot / Immunoblot ( WB )

Properties

ApplicationsDot blot ( Dot ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu )
PresentationIg Fraction
HostSheep
IsotypeIgG
Catalog NumberGTX29009
Quantity1 ml
Priceno delivery possible
DeliveryEurope only
ManufacturerGeneTex Inc.
DatasheetPDF-Download
http://www.genetex.com/co ...

Datasheet Extract

Laminin antibody
BackgroundLaminin, the most abundant structural and biologically active component in basement membranes, is a complex extracellular glycoprotein with an approximate molecular weight of 900 kD. It plays an important role in many aspects of the cell biology. Laminin is composed of one A chain (400 kD) one B1 chain (215 kD) and one B2 chain (205 kD) all held together by disulfide bonds. The molecule has a cross-like form with globular units near the ends of each chain, the sites where it is bound to Collagen IV, heparan sulfate, proteoglycan as well as to the surface of epithelial cells. Laminins from various species have common antigenic determinants. Laminin is only found in significant quantities in basement membranes, the thin extracellular matrices that surround epithelial tissue, nerve, fat cells and smooth, striated and cardiac muscle. It has been found to modulate cell differentiation, cell shaping and also cell movement because it appears to be an important cell substrate-adhesion protein. Variations in the expression of this protein have been observed in embryogenesis, organogenesis, post traumatic healing and cancer. The greatest interest in laminin has been provoked by the discovery of its ability to promote neurite regeneration.
ImmunogenHuman Laminin purified from human placenta which likely contained a mixture of multiple laminin isoforms. The main reactivity seems to be with laminin beta 1 and gamma 1 chains.
Format
Purification: IgG fraction
Purity: IgG fraction
BufferSystem: Glycine buffered saline pH7.4, 0.1% Sodium Azide, 0.1% EACA, 0.01% Benzamidine,1mM EDTA
ApplicationsDot, WB
SpecificityHuman - Not yet tested in other species
StorageKeep as concentrated solution, aliquot and store at 4

7 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1456B Sheep IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1456F Sheep IgG (H&L)  
  Rabbit FITC   2 mg / US$ 295
   
R1456T Sheep IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 295
   
R1456TR Sheep IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 305
   
R1456HRP Sheep IgG (H&L)  
  Rabbit HRP   2 mg / US$ 325
   
R1456AP Sheep IgG (H&L)  
  Rabbit AP   1 mg / US$ 345
   
R1433R Sheep IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 465
   

Click here to see all secondary antibodies for 'GTX29009 Laminin'.