GTX29665 ILP2 peptide antigen
50 µg / no delivery possible
Quick Overview
ILP2 peptide
Product Description
ILP2 peptide
Properties
| Catalog Number | GTX29665 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| ILP2 peptide | |
| Concentration | 0.2 mg/ml |
| Background | Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9. |
| Format | Purification: n/a Purity: n/a BufferSystem: PBS with 0.1% BSA 0.02% sodium azide pH7.2 |
| Applications | BL |
| Storage | Upon receipt - Keep as concentrated solution. Aliquot and store at -20 |
