GTX29676 Macrophage Inflammatory Protein 1 beta protein antigen
10 µg / no delivery possible
Quick Overview
Macrophage Inflammatory Protein 1 beta protein
Product Description
Macrophage Inflammatory Protein 1 beta protein
Properties
| Reactivity | Human ( Hu ) |
| Catalog Number | GTX29676 |
| Quantity | 10 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| Macrophage Inflammatory Protein 1 beta protein | |
| Background | MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD-5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated. |
| Immunogen | Highly pure (>98%) recombinant hIL-11 (human Interleukin-11) |
| Format | State: Lyophilized, no additives Purification: n/a Purity: n/a BufferSystem: n/a |
| Specificity | Human. Others not tested |
| Storage | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 |
