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GTX82982  Voltage-gated potassium channel subunit Kv1.2 antigen


see all 6 Voltage-gated potassium channel subunit Kv1.2 products
40 µg / no delivery possible
please contact the manufacturer
GeneTex Inc.
San Antonio, TX, USA
www.genetex.com

Quick Overview

Voltage-gated potassium channel subunit Kv1.2

Synonyms

KCNA2, HBK5, NGK1, HUKIV, Potassium voltage-gated channel subfamily A member 2,

Product Description

Voltage-gated potassium channel subunit Kv1.2

Properties

Catalog NumberGTX82982
Swiss Prot. No.P16389
Quantity40 µg
Priceno delivery possible
DeliveryEurope only
ManufacturerGeneTex Inc.
DatasheetPDF-Download
http://www.genetex.com/co ...

Datasheet Extract

Kv1.2 protein
BackgroundPPotassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homologs. This protein belongs to the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. Kv1.2 is a homologue of the Drosophila protein, Shaker, which is involved in reduced sleep and life expectancy.
Immunogen
Swiss Num.: P16389
Format
State: Liquid
BufferSystem: Phosphate-buffered saline, pH 7.2, containing no preservatives
ApplicationsWB
StorageKeep as concentrated solution. Aliquot and store at -80