NB100-177 Rad51C antibody
see related secondary antibodiessee all 10 Rad51C products
0.1 ml / US$ 435 no delivery possible
Quick Overview
Mouse anti Rad51C 2H11/6
Product Description
Mouse anti Rad51C 2H11/6, Presentation: Ascites. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Ascites |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | 2H11/6 |
| Catalog Number | NB100-177 |
| Quantity | 0.1 ml |
| Price | US$ 435 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet | view  NB100-177.pdf |
Datasheet Extract
| Mouse Monoclonal anti-RAD51C (2H11/6) | |
| Alternate names | anti-DNA repair protein Rad51 homolog 3 antibody; anti-Rad51 homolog C (S. cerevisiae) antibody; anti-Rad51L2 antibody; anti-Yeast Rad51 homolog 3 antibody |
| Background | The Rad51 DNA repair protein is a key component of the double-strand break repair pathway and is essential for mitotic and meiotic recombination and genomic stability.
Five human Rad51 homologs have been identified: XRCC2, XRCC3, Rad51B, Rad51C, and Rad51D. Each of these homologs interacts with one or more of the others, with all of the proteins involved in one complex, or with multiple smaller complexes. |
| Immunogen | His-tagged human Rad51C, over-expressed in E. coli. |
| Format | Purification: IgG purified Purity: IgG purified BufferSystem: PBS (physiological pH) |
| Applications | Western Blot 1:1000 |
| Specificity | Species: NB 100-177 recognizes human and mouse Rad51C. Other species have not been tested. NB 100-177 does not cross-react with Rad51B, Rad51D, Rad51, XRCC2, or XRCC3 in Western analysis. |
| Storage | Store at 4C. Do not freeze. |
| References | 1. Masson, et al. Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes & Dev. 15: 3296-3307 (2001) [Immunoprecipitation, human]
2. Maacke, H. Autoantibodies in sera of pancreatic cancer patients identify recombination factor Rad 51 as a tumour-associated antigen. J. Cancer Res. 128: 219-222 (2002) [Immunohistochemistry, Western Blot, Human] 3. Lambert, S. Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells. Oncogene. 21: 4065-4069 (2002) [Hamster] 4. Masson, et al. Complex formation by the human RAD51C and XRCC3 recombination repair proteins. PNAS. 98: 8440-8446 (2001) [Western Blot, Immunoprecipitation, Human] 5. Dosanjh, et al. Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes. Nuc. Acid Res. 26: 1179-1184 (1998) [Yeast] 6. Liu, Y., et al. RAD51C Is Required for Holliday Junction Processing in Mammalian Cells. SCIENCE.303: 243-246 (2004) [Human] 7. French, C.A. et al. Role of mammalian Rad51L2 (Rad51C) in recombination and genetic stability. 277(22): 19322-19330 (2002) [Western Blot, Immunoflouroescence, Immunoprecipitation, Human] 8. Godthelp, B.C. et al. Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability. Nuc. Acid Res. 30(10): 2172-2182 (2002) [Western Blot, Immunofluorescence, Hamster] 9.Kuznetsov, S., et al. RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females. J. Cell Biol. 176: 581-592 (2007) 10. Nagaraju, G., et al. Differential Regulation of Short- and Long-Tract Gene Conversion between Sister Chromatids by Rad51C. Mol. and Cell. Biol. 26: 8075-8086 (2006) |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-177 Rad51C'.
