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NB100-177SS  RAD51C antibody

see related secondary antibodies
see all 10 RAD51C products
0.025 ml / US$ 295 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Mouse anti RAD51C 2H11/6

Synonyms

anti-DNA repair protein RAD51 homolog 3 antibody; anti-RAD51 homolog C antibody; anti-RAD51L2 antibody; anti-Yeast RAD51 homolog 3 antibody, S. cerevisiae

Product Description

Mouse anti RAD51C 2H11/6, Presentation: Purified. Product is tested for Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )

Properties

ApplicationsImmunofluorescence ( IF ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu ), Mouse ( Ms )
PresentationPurified
HostMouse
IsotypeIgG1
Clone2H11/6
Catalog NumberNB100-177SS
Quantity0.025 ml
PriceUS$ 295 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Mouse Monoclonal anti-RAD51C (2H11/6)
Alternate namesanti-DNA repair protein RAD51 homolog 3 antibody, anti-RAD51 homolog C (S. cerevisiae) antibody, anti-RAD51L2 antibody, anti-Yeast RAD51 homolog 3 antibody
BackgroundThe Rad51 DNA repair protein is a key component of the double-strand break repair pathway and is essential for mitotic and meiotic recombination and genome stability.
Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homologs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes.
ImmunogenHis-tagged human Rad51C, over-expressed in E. coli.
Format
Purification: IgG purified
Purity: IgG purified
BufferSystem: PBS (physiological pH)
ApplicationsIF, WB
Specificity
Species: NB 100-177 recognizes human and mouse Rad51C. Other species have not been tested. NB 100-177 does not cross-react with Rad51B, Rad51D, Rad51, XRCC2, or XRCC3 in Western analysis.
StorageStore at 4C. Do not freeze.
References 1. Masson, et al. Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes & Dev. 15: 3296-3307 (2001) [Immunoprecipitation, human]
2. Maacke, H. Autoantibodies in sera of pancreatic cancer patients identify recombination factor Rad 51 as a tumour-associated antigen. J. Cancer Res. 128: 219-222 (2002) [Immunohistochemistry, Western Blot, Human]
3. Lambert, S. Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells. Oncogene. 21: 4065-4069 (2002) [Hamster]
4. Masson, et al. Complex formation by the human RAD51C and XRCC3 recombination repair proteins. PNAS. 98: 8440-8446 (2001) [Western Blot, Immunoprecipitation, Human]
5. Dosanjh, et al. Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes. Nuc. Acid Res. 26: 1179-1184 (1998) [Yeast]
6. Liu, Y., et al. RAD51C Is Required for Holliday Junction Processing in Mammalian Cells. SCIENCE.303: 243-246 (2004) [Human]
7. French, C.A. et al. Role of mammalian Rad51L2 (Rad51C) in recombination and genetic stability. 277(22): 19322-19330 (2002) [Western Blot, Immunoflouroescence, Immunoprecipitation, Human]
8. Godthelp, B.C. et al. Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability. Nuc. Acid Res. 30(10): 2172-2182 (2002) [Western Blot, Immunofluorescence, Hamster]
9.Kuznetsov, S., et al. RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females. J. Cell Biol. 176: 581-592 (2007)
10. Nagaraju, G., et al. Differential Regulation of Short- and Long-Tract Gene Conversion between Sister Chromatids by Rad51C. Mol. and Cell. Biol. 26: 8075-8086 (2006)

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1253B Mouse IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1253F Mouse IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1253T Mouse IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1253TR Mouse IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1253HRP Mouse IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1253AP Mouse IgG (H&L)  
  Rabbit AP   1 mg / US$ 325
   
R1457C2 Mouse IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1457C3 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1457C35 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1457C5 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1457C55 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1405R Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   
R1403R Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins  
  Rabbit PE   1 ml / US$ 455
   
R1455R Mouse IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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