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NB100-1973  Superoxide Dismutase 1 / SOD1 antibody

see related secondary antibodies
see all 50 Superoxide Dismutase 1 / SOD1 products
50 µg / US$ 485 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Rabbit anti Superoxide Dismutase 1 / SOD1

Synonyms

Superoxide dismutase [Cu-Zn], SOD-1, CuZn-SOD, CuZnSOD, IPOA, ALS1, , amyotrophic lateral sclerosis 1 adult

Product review
Please read our product review about Superoxide Dismutase 1 / SOD1: Antibody Panel to proteins of the superoxide dismutase enzyme family (SOD1, SOD2, SOD3, SOD4).

Product Description

Rabbit anti Superoxide Dismutase 1 / SOD1 , Presentation: Aff - Purified. Product is tested for Frozen sections ( C ), Enzyme Immunoassay ( E ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )

Properties

ApplicationsFrozen sections ( C ), Enzyme Immunoassay ( E ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu ), Mouse ( Ms ), Rat ( Rt ), Xenopus ( Xen ), Bovine ( Bov ), Canine ( Can ), Hamster ( Hst ), Monkey ( Mky ), Por ( Por ), Rabbit ( Rb ), Sheep ( Sh )
PresentationAff - Purified
HostRabbit
Catalog NumberNB100-1973
Swiss Prot. No.P07632
Quantity50 µg
PriceUS$ 485 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/p ...

Datasheet Extract

Rabbit Polyclonal anti-Cu/Zn SOD
Alternate namesanti-ALS 1 antibody, anti-ALS antibody, anti-ALS1 antibody, anti-Amyotrophic lateral sclerosis 1 antibody, anti-Homodimer antibody, anti-IPOA antibody, anti-SOD 1 antibody, anti-SOD antibody, anti-SOD1 antibody, anti-Soluble indophenoloxidase A antibody, anti-Superoxide dismutase 1 antibody, anti-Superoxide dismutase 1 soluble antibody, anti-Superoxide dismutase Cu Zn antibody
Concentration1 mg/ml
BackgroundSuperoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn SOD/SOD1), mitochondrial manganese SOD (Mn SOD/SOD2) and extracellular Cu, Zn SOD (EC SOD/SOD3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2 is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin binding multimer of disulfide linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase(CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
ImmunogenFull length protein (Rat).
Swiss Num.: P07632
Format
Purification: Immunogen affinity purified
Purity: Immunogen affinity purified
BufferSystem: 50% Glycerol, 0.1M Sodium Phosphate. pH 7.0
ApplicationsELISA, immunohistochemistry, immunoprecipitation, Western Blot
Specificity
Species: Cross-reacts with Human, Mouse, Rat, Xenopus laevis, Cow, Dog, Hamster, Monkey, Pig, Rabbit and Sheep. Not yet tested in other species.
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
ReferencesKurobe N et al. Sensitive enzyme immunoassay for human Cu/Zn superoxide dismutase. Clin Chim Acta 187:11-20 (1990). Kurobe N et al. Sensitive enzyme immunoassay for human Mn superoxide dismutase. Clin Chim Acta 192:171-9 (1990). Wong GH et al. Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor. Cell 58:923-31 (1989).

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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