NB100-1993 Dynamin-1 / DNM1 antibody
see related secondary antibodiessee all 12 Dynamin-1 / DNM1 products
50 µg / US$ 445 no delivery possible
Quick Overview
Mouse anti Dynamin-1 / DNM1 D5
Synonyms
Dynamin 1, DNM-1, DYN1, , B dynamin, Dynamin1
Product review
Please read our product review about Dynamin-1 / DNM1 : Antibodies to Dynamins.
Product Description
Mouse anti Dynamin-1 / DNM1 D5, Presentation: Purified. Product is tested for Frozen sections ( C ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ), Bovine ( Bov ), Chicken ( Chk ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG |
| Clone | D5 |
| Catalog Number | NB100-1993 |
| Swiss Prot. No. | Q05193 |
| Quantity | 50 µg |
| Price | US$ 445 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/p ... |
Datasheet Extract
| Mouse Monoclonal anti-Dynamin 1 (D5) | |
| Alternate names | anti-D100 antibody, anti-DNM antibody, anti-EC 3.6.5.5 antibody, anti-B dynamin antibody, anti-DNM 1 antibody, anti-DNM1 antibody, anti-Dynamin antibody, anti-Dynamin BREDNM19 antibody, anti-Dynamin1 antibody |
| Concentration | 0.55 mg/ml |
| Background | Dynamin is a 100 kDa GTP binding protein that was first identified as a protein able to bind microtubules (1). A mutation in the Drosophila gene shits, encoding a dynamin homologue, prevents synaptic vesicle recycling and causes temperature-sensitive paralysis, implicating dynamin in the formation of coated vesicles (2). Dynamin may mediate vesicle formation by assembling into a ring structure around the necks of invaginated coated pits that may eventually lead to the closure of the neck and formation of vesicles (3). Amphiphysin, dynamin, clathrin and AP2 form a complex during synaptic vesicle endocytosis, which is regulated by the phosphorylated state of different components in this complex (4). To date, three genes have been found to encode dynamin isoforms. Dynamin 1 is neuronal specific, Dynamin 2 is ubiquitously expressed and Dynamin 3 localizes to testis, brain and lung (5). |
| Immunogen | Recombinant His-tagged fusion protein, corresponding to amino acids 1-750 of Human Dynamin. Swiss Num.: Q05193 |
| Format | Purification: protein G purified Purity: protein G purified BufferSystem: PBS pH7.2, 0.1mM PMSF and 50% glycerol |
| Applications | flow cytometry / FACS analysis 10 ìg/mL, immunohistochemistry 1:50, immunoprecipitation , Western Blot 0.5 mg/mL |
| Specificity | Species: Cross-reacts with Human, Mouse, Rat, Cow and Chicken. Not yet tested in other species. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| References | 1. Shpetner, H.S. and Vallee, R.B. (1989) Cell 59: 421-432.
2. van der Bliek, A.M. and Meyerowitz, E.M. (1991) Nature 351: 411-414. 3. Takei, K., McPherson, P.S., Schmid, S.L., and Ce Camilli, P. (1995) Nature 374: 186-190. 4. Slepnev, V.I., Ochoa, G.-C., Butler, M.H., Grabs, D. and De Camilli, P. (1998) Science 281: 821-824. 5. Cao, H., Garcia, F., McNiven, M.A. (1998) Mol. Biol. Cell. 9: 2595-2609. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-1993 Dynamin-1 / DNM1 '.
