NB100-411 Fanconi anemia group D2 protein antibody
see related secondary antibodiessee all 16 Fanconi anemia group D2 protein products
0.1 mg / US$ 455 no delivery possible
Quick Overview
Mouse anti Fanconi anemia group D2 protein 103
Synonyms
FANCD2, FACD,
Product Description
Mouse anti Fanconi anemia group D2 protein 103, Presentation: Purified. Product is tested for Enzyme Immunoassay ( E ), Western blot / Immunoblot ( WB )
Properties
| Applications | Enzyme Immunoassay ( E ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG |
| Clone | 103 |
| Catalog Number | NB100-411 |
| Swiss Prot. No. | Q9BXW9 |
| Quantity | 0.1 mg |
| Price | US$ 455 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/p ... |
Datasheet Extract
| Mouse Monoclonal anti-FANCD2 (103) | |
| Alternate names | anti-FA4 antibody, anti-FACD antibody, anti-FAD antibody, anti-FAD2 antibody, anti-FANCD antibody, anti-FANCONI ANEMIA COMPLEMENTATION GROUP D antibody, anti-FANCONI PANCYTOPENIA TYPE 4 antibody |
| Concentration | 1 mg/ml |
| Background | Fanconi anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANCD2, targeting nuclear foci containing the BRCA1 protein. |
| Immunogen | Human FANCD2 fusion protein. Swiss Num.: Q9BXW9 |
| Format | Purification: protein G purified Purity: protein G purified BufferSystem: PBS, pH 7.2 |
| Applications | Western Blot, ELISA |
| Specificity | Species: Reacts with human FANCD2. Other species have not been tested. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| References | 1. Strahdee, C.A., et al. Evidence for at least four fanconi anaemia genes including FACC on chromosome 9. Nature Genet. 1:196-198, 1992.
2. Timmers, C., et al. Positional cloning of a novel fanconi anemia gene, FANCD2. Molec. Cell. 7:241-248, 2001. (Western Blot, human) 3. Garcia-Higuera, I. et al. Interaction of the fanconi anemia proteins and BRCA1 in a common pathway. Molec. Cell. 7:249-262, 2001. (Western Blot, Immunoprecipitation, human) 4. Nakanishi, K. et al. Interaction of FANCD2 and NBS1 i nthe DNA damage response. Nature Cell Bio. 4:913-920, 2002. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-411 Fanconi anemia group D2 protein'.
