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NB100-56618  Death receptor 5 (C-term) antibody

see related secondary antibodies
0.2 ml / US$ 485 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Rabbit anti Death receptor 5

Synonyms

anti-TRAILR2 antibody, TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily member 10B

Product Description

Rabbit anti Death receptor 5 , Presentation: Aff - Purified

Properties

ReactivityHuman ( Hu )
PresentationAff - Purified
HostRabbit
IsotypeIgG
Catalog NumberNB100-56618
Swiss Prot. No.O14763
Quantity0.2 ml
PriceUS$ 485 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Rabbit Polyclonal anti-DR5 (CT)
Alternate namesanti-TRAILR2 antibody
BackgroundApoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently (1-2). Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB.
ImmunogenRabbit anti-DR5 polyclonal antibody was raised against a peptide corresponding to amino acids 388 to 407 (isoform 2) of human DR5 precursor (1,2). The same sequence is found in isoform 1 at amino acids 417-436.
Swiss Num.: O14763
Format
Purification: Affinity Purified
Purity: Affinity Purified
BufferSystem: PBS containing 0.2% gelatin, 0.05% sodium azide. Sodium azide is highly toxic.
ApplicationsFACS IF ICC IHC WB
Specificity
Species: Human Not yet tested in other species.

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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