NB100-78273 FAK antibody
see related secondary antibodiessee all 68 FAK products
0.2 ml / US$ 495 no delivery possible
Quick Overview
Rabbit anti FAK
Synonyms
Protein-Tyrosine kinase, PTK2, FAK1, pp125FAK, FADK 1, , Focal Adhesion kinase 1, FAK-1, FADK1, FADK-1, Protein-tyrosine kinase 2
Product review
Please read our product review about FAK: Antibodies to Focal Adhesion Kinase (FAK).
Product Description
Rabbit anti FAK , Presentation: Aff - Purified. Product is tested for Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Mouse ( Ms ), Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | NB100-78273 |
| Swiss Prot. No. | Q05397 |
| Quantity | 0.2 ml |
| Price | US$ 495 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-FAK | |
| Alternate names | anti-IL-10R antibody, anti-Interleukin-10 Receptor antibody |
| Background | Focal adhesion kinase or FAK is a 125 kD non-receptor tyrosine kinase containing a FAT domain. This kinase localizes to focal adhesion sites after cell adhesion to matrix and shows ubiquitous distribution with highest expression in the brain and lowest expression in the heart and skeletal muscle. FAK is involved in the signaling pathways for cell motility, and proliferation, and apoptosis. Increased FAK kinase activity has been proposed to play a role in oncogenic transformation. FAK is activated by tyrosine-phosphorylation on multiple residues in response to either integrin clustering or G-protein coupled receptor activation (bombesin, lysophosphatidic acid) or LDL receptor activation. FAK has been reported to interact with p130-Cas,Grb2, c-Src, STAT1, integrin beta1 and beta2, ezrin, and paxillin. Alternate splice variants of FAK have been reported. The Poly6038 antibody recognizes human and mouse FAK and has been shown to be useful for Western blotting. |
| Immunogen | Recombinant (partial) , N-terminal Swiss Num.: Q05397 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| Applications | immunofluorescence, Western Blot |
| Specificity | Species: Mouse, Human. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Schaller, M., et al., 1992. PNAS. 89:5192. 2. Polte, T., et al., 1995. PNAS. 92:10678. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-78273 FAK'.
