NB100-78389 Cytokeratin-18 (KRT18) antibody
see related secondary antibodiessee all 69 Cytokeratin-18 products
0.2 ml / US$ 495 no delivery possible
Quick Overview
Rabbit anti Cytokeratin-18 (KRT18)
Synonyms
anti-Keratin 18 antibody antibody, anti-anti-Keratin type I cytoskeletal 18 antibody, Cell proliferation-inducing gene 46 protein
Product Description
Rabbit anti Cytokeratin-18 (KRT18) , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Mouse ( Ms ), Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | NB100-78389 |
| Swiss Prot. No. | P05783 |
| Quantity | 0.2 ml |
| Price | US$ 495 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-Keratin 18 | |
| Alternate names | anti-IL-10R antibody, anti-Interleukin-10 Receptor antibody |
| Background | Keratin 18 (also know as cytokeratin 18) is a 48 kD member of the Type I intermediate filament family, that forms heterotetramers. Keratin 18 is widely expressed in normal single layer epithelial tissues (liver, pancreas) and is expressed at high levels in some tumor tissues. Keratin 18 and filament partner keratin 8 are the most common members of intermediate filament family. Mutations in keratin 18 have been linked to cryptogenic cirrhosis. This protein is induced by retinoic acid, estrogen (breast cancer cells), and the Ras-signaling pathway (Ha-Ras, activated Src, Lck, Raf). Keratin 18 can be modified by phosphorylation, glycosylation, and ubiquitination. The active heterotetramer consists of two type I and two type II keratins (type I is acidic 40-55 kD, type II is neutral to basic 56-70 kD). Keratin 18 has been shown to associate with keratin 8, Mrj (a DnaJ/HSP40 family protein), and Hsp70. The Poly6172 antibody recognizes human and mouse keratin 18 and is useful for Western blotting. |
| Immunogen | Recombinant (partial), C-terminal Swiss Num.: P05783 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| Applications | Western Blot |
| Specificity | Species: Mouse, Human. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Izawa, I., et al., 2000. J. Biol. Chem. 275:34521. 2. Pankov, R., et al., 1994. PNAS 91:873. 3. Kulesh, D., et al.,1988. Mol. Cell. Biol. 8:1540. 4. Ku, N., et al., 1997. J. Clin. Invest. 99:19. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-78389 Cytokeratin-18 (KRT18)'.
