NB100-78591 CBL antibody
see related secondary antibodiessee all 22 CBL products
0.1 mg / US$ 485 no delivery possible
Quick Overview
Rabbit anti CBL
Synonyms
anti-C CBL antibody, anti-Cas-Br-M ecotropic retroviral transforming sequence antibody, anti-Casitas B lineage lymphoma proto oncogene antibody, anti-CBL 2 antibody, # CBL2 antibody, anti-E3 ubiquitin protein ligase CBL antibody, anti-Oncogene CBL2 antibody, anti-Proto oncogene c CBL antibody, anti-RING finger protein 55 antibody, anti-RNF55 antibody, anti-Signal transduction protein CBL antibody, murine
Product Description
Rabbit anti CBL , Presentation: Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | NB100-78591 |
| Quantity | 0.1 mg |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-CBL | |
| Alternate names | anti-C CBL antibody, anti-Cas-Br-M (murine) ecotropic retroviral transforming sequence antibody, anti-Casitas B lineage lymphoma proto oncogene antibody, anti-CBL 2 antibody # CBL2 antibody, anti-E3 ubiquitin protein ligase CBL antibody, anti-Oncogene CBL2 antibody, anti-Proto oncogene c CBL antibody, anti-RING finger protein 55 antibody, anti-RNF55 antibody, anti-Signal transduction protein CBL antibody |
| Concentration | 1 mg/ml |
| Background | The proto-oncogene c-CBL was initially identified as the cellular homologue of v-CBL oncogene that induces pre-B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap-70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL?s interaction with downstream targets of tyrosine kinases, such as PI-3K and Vav. |
| Immunogen | Synthetic peptide - Containing amino acids between 850-1000. |
| Format | Purification: protein A purified Purity: protein A purified BufferSystem: Phosphate-buffered saline, pH 7.2 |
| Applications | Western Blot 1:2, 000-1:10, 000 |
| Specificity | Species: Human. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-78591 CBL'.
