NB100-794 XAB2 antibody
see related secondary antibodiessee all 13 XAB2 products
0.1 mg / US$ 465 no delivery possible
Quick Overview
Goat anti XAB2
Synonyms
anti-Homolog of yeast Tim50 antibody, anti-TIM50 antibody, anti-Tim50 like protein antibody, anti-TIM50L antibody, anti-Translocase of inner mitochondrial membrane 50 homolog antibody, anti-DKFZp762C1015 antibody, anti-HCNP antibody, anti-HCRN antibody, anti-NTC90 antibody, anti-SYF1 antibody, yeast
Product Description
Goat anti XAB2 , Presentation: Aff - Purified
Properties
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Goat |
| Isotype | IgG |
| Catalog Number | NB100-794 |
| Quantity | 0.1 mg |
| Price | US$ 465 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Goat Polyclonal anti-XAB2 | |
| Alternate names | anti-Homolog of yeast Tim50 antibody, anti-TIM50 antibody, anti-Tim50 like protein antibody, anti-TIM50L antibody, anti-Translocase of inner mitochondrial membrane 50 homolog (yeast) antibody, anti-DKFZp762C1015 antibody, anti-HCNP antibody, anti-HCRN antibody, anti-NTC90 antibody, anti-SYF1 antibody |
| Concentration | 0.5 mg/ml |
| Background | Tim50 is a component of the yeast Tim23 import machinery, which mediates translocation of presequence containing proteins across the mitochondrial inner membrane. By searching sequence databases, open reading frames encoding proteins with similarity to Tim50 and with a putative mitochondrial presequence were identified in the genomes of evolutionarily distant organisms, including human. Tim50 was found to interact with the N terminal intermembrane space domain of Tim23. Functional defects of Tim50 either by depletion of the protein or addition of anti Tim50 antibodies blocked the protein translocation across the inner membrane. A translocation intermediate accumulated at the translocator of the outer mitochondrial membrane (TOM) complex was cross linked to Tim50. Thus it can be concluded that Tim50, in cooperation with Tim23, facilitates transfer of the translocating protein from the TOM complex to the Tim23 complex. |
| Immunogen | Synthetic peptide SVPAAVFGSLKED, representing the C terminus of the human protein (residues 843-855) of Human XAB2. |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Tris saline containing [pH7.3] with 0.5% BSA |
| Specificity | Species: Reacts with Human. Predicted to react with Mouse (100% identity with immunogen), Rat (100% identity with immunogen), Dog and Zebrafish (83% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| References | Nakatsu Y et al. XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription. J Biol Chem 275:34931-7 (2000). |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1317B | Goat IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 295 | |||||
| R1317F | Goat IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 295 | |||||
| R1317T | Goat IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 295 | |||||
| R1317TR | Goat IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1317HRP | Goat IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 305 | |||||
| R1317AP | Goat IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 315 | |||||
| R1435C2 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy2 | 1 mg / US$ 445 | |||||
| R1435C3 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3 | 1 mg / US$ 445 | |||||
| R1435C35 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3.5 | 1 mg / US$ 445 | |||||
| R1435C5 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5 | 1 mg / US$ 465 | |||||
| R1435C55 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5.5 | 1 mg / US$ 445 | |||||
| R1416R | Goat IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-794 XAB2'.
