NB100-79860 DFF45 / ICAD / DFFA antibody
see related secondary antibodiessee all 40 DFF45 / ICAD / DFFA products
0.1 ml / US$ 585 no delivery possible
Quick Overview
Rabbit anti DFF45 / ICAD / DFFA
Synonyms
anti-DFF45 antibody, anti-DFF-45 antibody, anti-DFFA antibody, anti-DNA fragmentation factor antibody, anti-45kDa antibody, anti-alpha polypeptide antibody, anti-ICAD antibody, anti-Inhibitor of CAD antibody, anti-DFF1 antibody, anti-DNA fragmentation factor 1 antibody, DNA fragmentation factor subunit alpha, DNA fragmentation factor 45 kDa subunit
Product Description
Rabbit anti DFF45 / ICAD / DFFA , Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | NB100-79860 |
| Swiss Prot. No. | O00273 |
| Quantity | 0.1 ml |
| Price | US$ 585 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-DFFA | |
| Alternate names | anti-DFF45 antibody, anti-DFF-45 antibody, anti-DFFA antibody, anti-DNA fragmentation factor antibody, anti-45kDa antibody, anti-alpha polypeptide antibody, anti-ICAD antibody, anti-Inhibitor of CAD antibody, anti-DFF1 antibody, anti-DNA fragmentation factor 1 antibody |
| Background | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Immunogen | The epitope recognized by this antibody maps to a region between residue 271 and 331 of human DNA fragmentation factor, 45kDa, alpha polypeptide using the numbering given in entry NP_004392.1 (GeneID 1676). Swiss Num.: O00273 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Tris-buffered Saline containing 0.1% BSA |
| Applications | Immunohistochemistry-Paraffin 1:100-1:500 |
| Specificity | Species: Human |
| Storage | Store at 4C. Do not freeze. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-79860 DFF45 / ICAD / DFFA'.
