NB100-80050 Superoxide Dismutase 1 / SOD1 antibody
see related secondary antibodiessee all 49 Superoxide Dismutase 1 / SOD1 products
0.1 ml / US$ 485 no delivery possible
Quick Overview
Rabbit anti Superoxide Dismutase 1 / SOD1
Synonyms
Superoxide dismutase [Cu-Zn], SOD-1, CuZn-SOD, CuZnSOD, IPOA, ALS1, , amyotrophic lateral sclerosis 1 adult
Product review
Please read our product review about Superoxide Dismutase 1 / SOD1: Antibody Panel to proteins of the superoxide dismutase enzyme family (SOD1, SOD2, SOD3, SOD4).
Product Description
Rabbit anti Superoxide Dismutase 1 / SOD1 , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB ), Frozen sections ( C ), Immunofluorescence ( IF ), Immunoprecipitation ( IP )
Properties
| Applications | Western blot / Immunoblot ( WB ), Frozen sections ( C ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | NB100-80050 |
| Swiss Prot. No. | P00441 |
| Quantity | 0.1 ml |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-SOD1 | |
| Alternate names | Anti- antibody |
| Background | The eukaryotic copper,zinc superoxide dismutases are remarkably stable dimeric proteins that maintain an intrasubunit disulfide bond in the reducing environment of the cytosol and are active under a variety of stringent denaturing conditions. The structural interplay of conserved disulfide bond and metal-site occupancy in human copper,zinc superoxide dismutase (SOD1) is of increasing interest as these post-translational modifications are known to dramatically alter the catalytic chemistry, the subcellular localization, and the susceptibility of the protein to aggregation (1). Defective SOD is linked to motor neuron death and carries implications for understanding and possible treatment of the fatal neurodegenerative disorder familial amyotrophic lateral sclerosis (FALS). A crystal structure of human SOD, along with two other SOD structures, established that all 12 observed FALS mutant sites alter conserved interactions critical to the beta-barrel fold and dimer contact, rather than catalysis (2). |
| Immunogen | A synthetic peptide corresponding to residues near the N-terminus of human SOD1 was used as an immunogen. Swiss Num.: P00441 |
| Format | Purification: Affinity purified Purity: Affinity purified |
| Applications | Western Blot 1:5000,immunohistochemistry 1:50-100,Immunocytochemistry 1:50-100,immunoprecipitation 1:20 |
| Specificity | Species: This antibody is reactive against Human |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Arnesano F, et al. J Biol Chem 279(46):47998-8003, 2004 2. Deng HX, et al. Science 261(5124):1047-51, 1993. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-80050 Superoxide Dismutase 1 / SOD1'.
