NB100-80870 CD243 / ABCB1 / MDR1 antibody
see related secondary antibodiessee all 17 CD243 / ABCB1 / MDR1 products
0.05 mg / US$ 515 no delivery possible
Quick Overview
Rabbit anti CD243 / ABCB1 / MDR1
Synonyms
Multidrug resistance protein 1, P-glycoprotein 1, CD243, PGY1, MDR1, EC 3.6.3.44, ABCB1, ATP-binding cassette sub-family B member 1
Product Description
Rabbit anti CD243 / ABCB1 / MDR1 , Presentation: Aff - Purified. Product is tested for Frozen sections ( C ), Western blot / Immunoblot ( WB ), Enzyme Immunoassay ( E )
Properties
| Applications | Frozen sections ( C ), Western blot / Immunoblot ( WB ), Enzyme Immunoassay ( E ) |
| Reactivity | Canine ( Can ), Human ( Hu ), Monkey ( Mky ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | NB100-80870 |
| Swiss Prot. No. | P08183 |
| Quantity | 0.05 mg |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-P Glycoprotein | |
| Alternate names | anti-ABCB1 antibody, anti-ABC20 antibody, anti-CD243 antibody, anti-CLCS antibody, anti-EC 3.6.3.44 antibody, anti-GP170 antibody, anti-MDR1 antibody, anti-P-GP antibody, anti-PGY1 antibody, anti-ATP binding cassette sub family B MDR/TAP member 1 antibody |
| Concentration | 1.28 mg/ml |
| Background | P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas. |
| Immunogen | Synthetic peptide; Amino acids 262-277 of human ABCB1 protein. Swiss Num.: P08183 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
| Applications | immunohistochemistry 5 ug/ml,,Western Blot 1:200-1:2000,,ELISA 1:10000-1:50000, |
| Specificity | Species: This antibody is reactive against Dog, Human, Monkey, Mouse, Rat |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-80870 CD243 / ABCB1 / MDR1'.
