NB110-56949 EIF2A (pSer51) antibody
see related secondary antibodiessee all 26 EIF2A products
0.1 ml / US$ 535 no delivery possible
Quick Overview
Rabbit anti EIF2A (pSer51) E90
Synonyms
eIF-2A, eIF2-alpha, EIF2S1, , Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, CDA02, MST089, MSTP004, MSTP089
Product review
Please read our product review about EIF2A (pSer51): Antibodies to eukaryotic Initiation Factors (eIF).
Product Description
Rabbit anti EIF2A (pSer51) E90, Presentation: Aff - Purified. Product is tested for Flow cytometry ( F ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Flow cytometry ( F ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Clone | E90 |
| Catalog Number | NB110-56949 |
| Swiss Prot. No. | P05198 |
| Quantity | 0.1 ml |
| Price | US$ 535 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Monoclonal anti-Phospho-elF-2alpha (pS51) (E90) [Ser51] | |
| Alternate names | anti-CDA02 antibody, anti-eIF 2 alpha antibody, anti-EIF 2 antibody, anti-EIF 2A antibody, anti-EIF-2alpha antibody, anti-EIF2 antibody, anti-EIF2A antibody, anti-EIF2alpha antibody, anti-eIF2S1 antibody, anti-Eukaryotic Translation Initiation Factor 2 alpha antibody, anti-Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa antibody, anti-Eukaryotic translation initiation factor 2 subunit 1 antibody, anti-Eukaryotic translation initiation factor 2 subunit alpha antibody |
| Background | IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator. It is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities. Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER. |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser51 of human eIF-2a. Swiss Num.: P05198 |
| Format | Purification: Whole antisera Purity: Whole antisera BufferSystem: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Applications | immunohistochemistry 1:50?1:100, Western Blot 1:500-1:1000, Immunocytochemistry 1:100?1:250 |
| Specificity | Species: Reacts in Human, Mouse, and Rat. Not tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Ernst, H., et al. Cloning and sequencing of complementary DNAs encoding the alpha-subunit of translational initiation factor eIF-2. Characterization of the protein and its messenger RNA. J Biol Chem. 262: 1206?12 (1987). 2. Kimball, S.R. Eukaryotic initiation factor eIF2. Int. J. Biochem. Cell Biol. 31: 25?29 (1999). 3. De Haro, C., et al. The eIF-2alpha kinases and the control of protein synthesis. FASEB J. 10: 1378?1387 (1996). |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB110-56949 EIF2A (pSer51)'.
